Cao JD, Lin PH, Cai DF, Liang JH. Successful treatment of solitary bladder plasmacytoma: A case report . World J Clin Cases 2021; 9(25): 7453-7458 [PMID: 34616811 DOI: 10.12998/wjcc.v9.i25.7453]
Corresponding Author of This Article
Jia-Hua Liang, Surgeon, The Second Clinical College, Guangzhou University of Chinese Medicine, No. 12 Jichang Road, Guangzhou 510405, Guangdong Province, China. 283975468@qq.com
Research Domain of This Article
Oncology
Article-Type of This Article
Case Report
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Jia-Dong Cao, Department of Urology, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou 510105, Guangdong Province, China
Peng-Hui Lin, Dan-Feng Cai, Jia-Hua Liang, The Second Clinical College, Guangzhou University of Chinese Medicine, Guangzhou 510405, Guangdong Province, China
Author contributions: Cao JD conducted literature search, collected data, interpreted the data, and prepared the manuscript; Liang JH collected data, interpreted the data, edited the manuscript, and critically revised the draft; Cai DF interpreted the data and critically revised the draft; Lin PH designed the study, interpreted the data, edited the manuscript, and critically revised the draft.
Informed consent statement: The patient has given her written informed consent to publish the case (including publication of images).
Conflict-of-interest statement: The authors have no conflicts of interest to declare.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Jia-Hua Liang, Surgeon, The Second Clinical College, Guangzhou University of Chinese Medicine, No. 12 Jichang Road, Guangzhou 510405, Guangdong Province, China. 283975468@qq.com
Received: December 28, 2020 Peer-review started: December 28, 2020 First decision: April 29, 2021 Revised: May 9, 2021 Accepted: July 7, 2021 Article in press: July 7, 2021 Published online: September 6, 2021 Processing time: 242 Days and 15 Hours
Abstract
BACKGROUND
Plasmacytoma is a rare neoplastic disorder that arises from B-lymphocytes. Solitary bladder plasmacytoma, a type of solitary extramedullary plasmacytoma, is even rarer. Treatments for solitary extramedullary plasmacytoma include surgery, chemotherapy, and radiation. However, there are no clinical trials or guidelines specifying which treatment might represent the gold standard.
CASE SUMMARY
We herein report a case of a 51-year-old woman with solitary bladder plasmacytoma (SBP). There remains no consensus regarding the optimal treatment for SBP. However, we successfully treated her with transurethral resection of bladder tumor followed by postoperative radiotherapy (50 Gy/25 F). The patient remained free of tumor recurrence at a 7-mo follow-up.
CONCLUSION
Radiation is the potential main treatment for SBP. However, surgery is also necessary.
Core Tip: Solitary bladder plasmacytoma is rare. At present, there is no consensus on the optimal treatment for this disease. Herein, we reviewed past case reports on SBP and suggested radiation as its main treatment based on our results. Furthermore, radiation combined with surgery may be better than radiation alone. In addition, close monitoring is as important as treatment, and monoclonal protein is significant to the prognosis of this disease.
