Published online Aug 26, 2021. doi: 10.12998/wjcc.v9.i24.7251
Peer-review started: April 25, 2021
First decision: May 24, 2021
Revised: June 2, 2021
Accepted: June 15, 2021
Article in press: June 15, 2021
Published online: August 26, 2021
Processing time: 120 Days and 22.9 Hours
The simultaneous occurrence of schwannoma and meningioma in the absence of neurofibromatosis (NF) or a previous history of irradiation is exceedingly rare, as only 10 intracranial cases have been reported to date. Herein, we report a case of a coexistent cavernous sinus meningioma and ipsilateral vestibular schwannoma (VS) in a female patient without NF or a history of exposure to irradiation.
A 63-year-old woman presented with progressive left-side hearing loss and tinnitus over the previous year. In the past 6 mo, she developed facial numbness and intermittent headaches. Magnetic resonance imaging showed two lesions that were located on the left side of the cerebellopontine angle and parasellar region. Both lesions were totally resected via the left retrosigmoid approach. Histopathological examination revealed a VS and a meningioma. The patient did not have a family history or clinical or radiological signs of NF.
The coincident occurrence of VS and meningioma within close vicinity is very rare, and the pathogenesis is unclear. A careful whole-body examination needs to be conducted to exclude NF. Surgical treatment with the goal of total tumor resection is the best therapy. Additional studies are needed for a better under
Core Tip: Coexistent schwannoma and meningioma in the absence of neurofibromatosis or a history of irradiation are extremely rare. To the best of our knowledge, only 10 intracranial cases have been reported to date. Herein, we present the case of a coexistent cavernous sinus meningioma and ipsilateral vestibular schwannoma (VS) in a 63-year-old woman. This is the first report of a concurrent meningioma outside of the cerebellopontine angle, along with a coexisting VS. The medical literature was reviewed and the typical histopathological and radiological features of this rare tumor are described, with a detailed discussion of the diagnosis, treatment, and prognosis.