Published online Aug 26, 2021. doi: 10.12998/wjcc.v9.i24.7181
Peer-review started: January 20, 2021
First decision: May 13, 2021
Revised: May 19, 2021
Accepted: July 6, 2021
Article in press: July 6, 2021
Published online: August 26, 2021
Gastric glomus tumor (GGT) is rare submucosal mesenchymal tumor that lacks specific clinical manifestations and is usually treated mainly by traditional surgical resection. This paper presents a case of a GGT, exhibited both intraluminally and extraluminally growth that was removed by laparoscopy-gastroscopy cooperative surgery.
A 52-year-old male presented with epigastric discomfort accompanied by a sense of fullness for 3 mo. Upper gastrointestinal endoscopy identified a submucosal lump located in the gastric antrum. Endoscopic ultrasonography identified a 2.4 cm × 1.8 cm lump located in the gastric antrum. It originated from the muscularis propria and exhibited both intraluminally and extraluminally growth, with hypoechoicity on the periphery, hyperechoicity in the middle, and unclear boundaries. Computed tomography showed nodular thickening of 3.0 cm × 2.2 cm in the gastric wall of the gastric antrum, and after enhancement, the lesion exhibited obvious enhancement We suspected that it was a gastrointestinal stromal tumor (glomus tumor and schwannoma were not excluded) and planned to perform laparoscopy-gastroscopy cooperative surgery. Immunohistochemical staining after the operation revealed that spinal muscular atrophy (+), h-caldesmon (+), cluster of differentiation 34 (CD34) (+), 2% Ki-67-positive rate, CD56, melanoma antigen, CD117, discovered on GIST-1, leukocyte common antigen, caudal type homeobox 2, cytokeratin, and S-100 were all negative. The tumor was finally diagnosed as a GGT.
GGTs are rare submucosal tumors of the stomach and should be considered in the differential diagnosis of gastric submucosal tumors. Laparoscopy-gastroscopy cooperative surgery is less invasive and more precise and could be an effective method for the treatment of GGTs.
Core Tip: Gastric glomus tumors (GGTs) lack specific clinical and endoscopic features. They are often mistaken as common gastrointestinal stromal tumors (GISTs), which means that they are difficult to diagnose preoperatively. Whereas laparoscopic resection can be performed in traditional surgery, it is difficult to accurately determine the location of the region growing into the cavity. Surgery is traumatic and invasive and can cause related complications. This paper presents a case of GGT that was removed by laparoscopy-gastroscopy cooperative surgery. We also reviewed the literature on computed tomography findings and traditional surgical methods of GISTs and GGTs.