Hsu HJ, Huang CC, Chuang MT, Tien CH, Lee JS, Lee PH. Recurrent inverted papilloma coexisted with skull base lymphoma: A case report. World J Clin Cases 2021; 9(2): 516-520 [PMID: 33521124 DOI: 10.12998/wjcc.v9.i2.516]
Corresponding Author of This Article
Po-Hsuan Lee, MD, Surgeon, Section of Neurosurgery, Department of Surgery, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, No. 138 Shengli Road, North District, Tainan 704, Taiwan. ftl053@gmail.com
Research Domain of This Article
Anatomy & Morphology
Article-Type of This Article
Case Report
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Clin Cases. Jan 16, 2021; 9(2): 516-520 Published online Jan 16, 2021. doi: 10.12998/wjcc.v9.i2.516
Recurrent inverted papilloma coexisted with skull base lymphoma: A case report
Heng Juei Hsu, Chi Chen Huang, Ming Tsung Chuang, Chih Hao Tien, Jung Shun Lee, Po-Hsuan Lee
Heng Juei Hsu, Section of Neurosurgery, Department of Surgery, Tainan Sin Lau Hospital, Tainan 70144, Taiwan
Chi Chen Huang, Chih Hao Tien, Jung Shun Lee, Po-Hsuan Lee, Section of Neurosurgery, Department of Surgery, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan 704, Taiwan
Ming Tsung Chuang, Department of Medical Imaging, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan 704, Taiwan
Jung Shun Lee, Department of Cell Biology and Anatomy, College of Medicine, National Cheng Kung University, Tainan 701, Taiwan
Author contributions: Lee PH and Lee JS were the patient’s neurosurgeons, reviewed the literature and contributed to manuscript drafting; Hsu HJ, Huang CC and Tien CH reviewed the literature and contributed to manuscript drafting; Chuang MT analyzed and interpreted the image findings; Hsu HJ and Lee JS were responsible for the revision of the manuscript for important intellectual content; all authors have read and approved the final manuscript.
Informed consent statement: Informed written consent was obtained from the patient for publication of this reporting.
Conflict-of-interest statement: The authors declare that they have no conflict of interest.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Po-Hsuan Lee, MD, Surgeon, Section of Neurosurgery, Department of Surgery, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, No. 138 Shengli Road, North District, Tainan 704, Taiwan. ftl053@gmail.com
Received: November 1, 2020 Peer-review started: November 1, 2020 First decision: November 20, 2020 Revised: November 26, 2020 Accepted: December 6, 2020 Article in press: December 6, 2020 Published online: January 16, 2021 Processing time: 68 Days and 4.5 Hours
Abstract
BACKGROUND
Inverted papilloma is an uncommon neoplasm in the nasal cavity. It is a histologically benign tumor, but has a high recurrence and local invasion rate. In addition, nasal or skull base lymphoma is another rare neoplasm. The coexistence of these two tumors in one case makes the diagnosis and related treatment difficult.
CASE SUMMARY
We report a case of an immunocompetent patient, who had a history of inverted papilloma 20 years ago. The patient presented with an infiltrated mass lesion in the nasal cavity with extension to the frontal base. The repeated biopsies revealed inverted papilloma without any malignant transformation. After the patient underwent a frontobasal craniotomy with total tumor excision, the final pathological examination revealed nasal inverted papilloma coexisting with diffuse large B-cell lymphoma of the skull base.
CONCLUSION
Based on this case report, while managing a case of an aggressive recurrent inverted papilloma, not only squamous cell carcinoma transformation, but also other invasive malignancy, such as lymphoma, should be considered.
Core Tip: Inverted papilloma is a neoplasm in the nasal cavity and has a high local invasion rate. In addition, nasal or skull base lymphoma is another rare neoplasm. The coexistence of these two tumors in one case makes the diagnosis and related treatment difficult. We report a case of an immunocompetent patient presented with an infiltrated mass lesion in the nasal cavity with extension to the frontal base. The pathological examination revealed nasal inverted papilloma coexisting with diffuse large B-cell lymphoma of the skull base. This is the first case of a coexisted nasal inverted papilloma with skull base lymphoma.
