Yi D, Zhao LJ, Ding XB, Wang TW, Liu SY. Clinical characteristics of intrahepatic biliary papilloma: A case report. World J Clin Cases 2021; 9(13): 3185-3193 [PMID: 33969107 DOI: 10.12998/wjcc.v9.i13.3185]
Corresponding Author of This Article
Song-Yang Liu, MD, PhD, Chief Physician, Professor, Department of Hepatobiliary and Pancreatic Surgery, The First Hospital of Jilin University, No. 71 Xinmin Street, Changchun 130021, China. liusongyang@126.com
Research Domain of This Article
Gastroenterology & Hepatology
Article-Type of This Article
Case Report
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Clin Cases. May 6, 2021; 9(13): 3185-3193 Published online May 6, 2021. doi: 10.12998/wjcc.v9.i13.3185
Clinical characteristics of intrahepatic biliary papilloma: A case report
Dan Yi, Li-Jing Zhao, Xiao-Bo Ding, Tai-Wei Wang, Song-Yang Liu
Dan Yi, Song-Yang Liu, Department of Hepatobiliary and Pancreatic Surgery, The First Hospital of Jilin University, Changchun 130012, Jilin Province, China
Li-Jing Zhao, Tai-Wei Wang, Department of Rehabilitation, School of Nursing, Jilin University, Changchun 130012, Jilin Province, China
Xiao-Bo Ding, Department of Radiology, The First Hospital of Jilin University, Changchun 130012, Jilin Province, China
Author contributions: Yi D was a major contributor to data acquisition, literature retrieval and manuscript writing; Ding XB contributed to the acquisition of screening and imaging data; Wang TW contributed to the analysis of materials and the modification of the manuscript; Zhao LJ and Liu SY made important modifications to the manuscript; All authors read and approved the final manuscript.
Informed consent statement: All included patients gave written and oral informed consent for publication.
Conflict-of-interest statement: The authors declare no conflicts of interest.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Song-Yang Liu, MD, PhD, Chief Physician, Professor, Department of Hepatobiliary and Pancreatic Surgery, The First Hospital of Jilin University, No. 71 Xinmin Street, Changchun 130021, China. liusongyang@126.com
Received: December 10, 2020 Peer-review started: December 10, 2020 First decision: January 27, 2021 Revised: January 30, 2021 Accepted: February 25, 2021 Article in press: February 25, 2021 Published online: May 6, 2021
Abstract
BACKGROUND
Intrahepatic bile duct papilloma (IPNB) is a rare benign tumour from the bile duct epithelium and has a high malignant transformation rate. Early radical resection can obviously improve the prognosis of patients, but it is difficult to be sure of the diagnosis of IPNB before operating.
CASE SUMMARY
This study included 28 patients with intraductal papilloma admitted to the First Hospital of Jilin University from January 2010 to November 2020 and recorded their clinical manifestations, imaging features, complications and prognosis. There were 12 males and 16 females with an average age of 61.36 ± 8.03 years. Most patients had symptoms of biliary obstruction. Biliary dilatation and cystic mass could be seen on imaging. After surgery, IPNB was diagnosed by pathology.
CONCLUSION
IPNB is a rare benign tumour in the bile duct. Early diagnosis and timely R0 resection can improve the prognosis of IPNB.
Core Tip: Intrahepatic bile duct papilloma (IPNB) is a rare benign tumour in the bile duct. An early radical operation can improve the prognosis. This study analysed the clinical manifestations, imaging features, complications and prognosis of IPNB. IPNB should be considered in patients with bile duct recurrent infection, cholestasis and biliary obstruction, if imaging examination shows cystic dilatation of the bile duct, if there are mural nodules or papillary tumours with delayed enhancement, if the cystic-solid tumours communicate with the bile duct and if the upstream and downstream bile ducts dilate.
