Jiang LL, Tong DM, Feng ZY, Liu KR. Mesonephric adenocarcinoma of the uterine cervix with rare lung metastases: A case report and review of the literature. World J Clin Cases 2020; 8(9): 1735-1744 [PMID: 32432147 DOI: 10.12998/wjcc.v8.i9.1735]
Corresponding Author of This Article
Kui-Ran Liu, PhD, Professor, Department of Obstetrics and Gynecology, Shengjing Hospital of China Medical University, No. 36, Sanhao Street, Shenyang 110004, Liaoning Province, China. liukr@sj-hospital.org
Research Domain of This Article
Obstetrics & Gynecology
Article-Type of This Article
Case Report
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Clin Cases. May 6, 2020; 8(9): 1735-1744 Published online May 6, 2020. doi: 10.12998/wjcc.v8.i9.1735
Mesonephric adenocarcinoma of the uterine cervix with rare lung metastases: A case report and review of the literature
Li-Li Jiang, De-Ming Tong, Zi-Yi Feng, Kui-Ran Liu
Li-Li Jiang, Kui-Ran Liu, Department of Obstetrics and Gynecology, Shengjing Hospital of China Medical University, Shenyang 110004, Liaoning Province, China
De-Ming Tong, Department of General Surgery, Northen War General Hospital Heping Branch Hospital, Shenyang 110004, Liaoning Province, China
Zi-Yi Feng, College of Clinical Medicine Science, China Medical University, Shenyang 110013, Liaoning Province, China
Author contributions: Jiang LL conducted a thorough literature review and was the major contributor in writing the manuscript; Tong DM and Feng ZY prepared the pathological sections and took the images; Liu KR was responsible for reviewing and revising the article.
Supported byClinical Medicine Peak Subject Supporting Program of China Medical University (2018, Gynecology), No. 3110118041.
Informed consent statement: Informed written consent was obtained from the patient for publication of this report and any accompanying images.
Conflict-of-interest statement: The authors declare that they have no conflict of interest.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: Kui-Ran Liu, PhD, Professor, Department of Obstetrics and Gynecology, Shengjing Hospital of China Medical University, No. 36, Sanhao Street, Shenyang 110004, Liaoning Province, China. liukr@sj-hospital.org
Received: January 13, 2020 Peer-review started: January 13, 2020 First decision: February 26, 2020 Revised: March 27, 2020 Accepted: April 18, 2020 Article in press: April 18, 2020 Published online: May 6, 2020 Processing time: 108 Days and 6.6 Hours
Abstract
BACKGROUND
Mesonephric adenocarcinoma (MNA) of the female reproductive system is a rare tumor arising from remnants of the mesonephric duct, which is mainly located in the cervix. MNA often occurs in adult women. Due to the rarity of the disease and few reports, the specific clinical features have not been established.
CASE SUMMARY
We present a case of a cervical MNA in a 48-year-old woman with an incidental intra-operative diagnosis who received postoperative chemotherapy. Rare lung metastases were detected during follow-up. The existing literature is reviewed.
CONCLUSION
The clinical manifestations, pathological characteristics, diagnosis, treatment, and prognosis of MNA have been summarized through the review of the existing literature and the case in this paper. Due to the rarity of this disease, it is very important for the research of MNA in the future.
Core tip: We evaluated a case of cervical mesonephric adenocarcinoma in a 48-year-old female who was accidentally found by surgery and received postoperative chemotherapy. Rare lung metastases appeared during follow-up. The disease is very rare and there have been only 48 cases reported in the literature since 1962. We performed a literature review to summarize the clinical manifestation, pathological characteristics, immunohistochemistry, treatment, and prognosis of the disease, in order to increase the experience of diagnosis and treatment and benefit patients.
