Published online Apr 6, 2020. doi: 10.12998/wjcc.v8.i7.1271
Peer-review started: December 9, 2019
First decision: January 7, 2020
Revised: January 13, 2020
Accepted: March 9, 2020
Article in press: March 9, 2020
Published online: April 6, 2020
Processing time: 118 Days and 17.6 Hours
Spinal intraosseous schwannomas (SIS) are rare, and as yet have not been fully described in the literature. The first case of SIS was reported in 1971, and 24 cases of SIS have been reported so far. However, including the present case, there are only seven cases without spinal canal and neuroforamina involvement.
A 56-year-old man presented with a history of neck pain for 2 years. An obvious osteolytic destruction of the seventh cervical (C7) vertebra was observed on imaging examination. Magnetic resonance imaging of the cervical spine showed space-occupying lesions in the C7 vertebra, and destruction of the anterior cortex of the vertebra. The lesions had an exophytic component that extended from the C7 vertebra into the soft tissue on the front side. The foramen transversarium on both sides were intact. The patient underwent surgical biopsy and focal excision of the C7 lesion. The diagnosis of “schwannoma” was verified by postoperative pathological examinations. In a review of the literature, this is the seventh case of SIS without spinal canal and neuroforamina involvement, and the third reported case of type VIII SIS. We discussed our case with respect to reported classification characteristics of SIS.
SIS is a very rare tumor. We report a rare case that may be important for further classification of osteo-schwannoma. The establishment of a complete disease classification is of high importance for the treatment and prognosis of this disease. Thus, more basic studies and retrospective analysis of related cases are necessary.
Core tip: Intraosseous schwannomas are extremely rare, accounting for < 0.2% of primary bone tumors. Spinal intraosseous schwannomas (SIS) are even rarer. We present a rare case of SIS of the seventh cervical (C7) vertebra in a 56-year-old man presenting with a history of neck pain for 2 years. An obvious osteolytic destruction of the C7 vertebra was observed on imaging examination. The patient underwent surgical biopsy and focal excision of the C7 lesion. The diagnosis of “schwannoma” was verified by postoperative pathological examinations. In a review of the literature, this is the seventh case of SIS without spinal canal and neuroforamina involvement, and the third case of type VIII SIS. It is important for further classification of osteo-schwannoma.