Li KY, Wei AL, Li A. Primary hepatic myelolipoma: A case report and review of the literature. World J Clin Cases 2020; 8(19): 4615-4623 [PMID: 33083426 DOI: 10.12998/wjcc.v8.i19.4615]
Corresponding Author of This Article
Ang Li, MD, PhD, Doctor, Professor, Surgeon, Department of Hepato-Bilio-Pancreatic Surgery, West China Hospital, Sichuan University, No. 35 Guoxue Alley, Wuhou District, Chengdu 610041, Sichuan Province, China. angli@scu.edu.cn
Research Domain of This Article
Gastroenterology & Hepatology
Article-Type of This Article
Case Report
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Clin Cases. Oct 6, 2020; 8(19): 4615-4623 Published online Oct 6, 2020. doi: 10.12998/wjcc.v8.i19.4615
Primary hepatic myelolipoma: A case report and review of the literature
Ke-Yu Li, Ai-Lin Wei, Ang Li
Ke-Yu Li, Ai-Lin Wei, Ang Li, Department of Hepato-Bilio-Pancreatic Surgery, West China Hospital, Sichuan University, Chengdu 610041, Sichuan Province, China
Author contributions: Li KY and Wei AL contributed to study concept and design; Li KY and Li A contributed to data collection; Wei AL and Li KY contributed to investigation and writing the original draft; Li A analyzed the data and revised the paper; all authors have read and approved the final version of this manuscript.
Supported byNational Natural Science Foundation of China, No. 81773174.
Informed consent statement: Written informed consent was obtained from the patient for publication of this case report and associated images.
Conflict-of-interest statement: The authors declare that they have no conflict of interest to disclose.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: Ang Li, MD, PhD, Doctor, Professor, Surgeon, Department of Hepato-Bilio-Pancreatic Surgery, West China Hospital, Sichuan University, No. 35 Guoxue Alley, Wuhou District, Chengdu 610041, Sichuan Province, China. angli@scu.edu.cn
Received: April 29, 2020 Peer-review started: April 29, 2020 First decision: May 21, 2020 Revised: June 1, 2020 Accepted: August 25, 2020 Article in press: August 25, 2020 Published online: October 6, 2020 Processing time: 151 Days and 8.9 Hours
Abstract
BACKGROUND
Primary hepatic myelolipoma is a rare hepatic mesenchymal tumor mixed by adipose tissue and bone marrow, and there is a lack of general guidelines related to its epidemiology and clinical management.
CASE SUMMARY
A 26-year-old woman was admitted to our department complaining of a newly found tumor on her left lobe of the liver. The tumor was painless and not associated with any systemic or localized compressive symptoms. Serological tests disclosed a slight increase of gamma-glutamyl transpeptidase (70.0 U/L) and total bilirubin (19.2 μmol/L). Ultrasonography showed a mass about 5.0 cm × 5.0 cm in size that was located in the left lobe of the liver and displayed hyperechoic and well-encapsulated characteristics. Surgical resection was applied, and the following histopathological examination observed a variable proportion of myeloid tissues scattering throughout mature fibrotic adipose tissues, in which myeloid, erythroid, and megakaryocytic cells can be found in magnified view. The follow-up did not show any changes 6 mo after surgery.
CONCLUSION
This case highlights an extremely rare hepatic mesenchymal tumor, the primary hepatic myelolipoma, and discloses the common characteristics behind this disease and gives clinical recommendations.
Core Tip: Primary hepatic myelolipoma is an extremely rare benign tumor composed of mature adipose tissue and hematopoietic elements. We present herein a case of asymptomatic primary hepatic myelolipoma and include another 24 previously published cases in our analysis, to disclose the common clinical characteristics behind this disease and give clinical recommendations.
