Wu DD, Hao KN, Chen XJ, Li XM, He XF. Application of ozonated water for treatment of gastro-thoracic fistula after comprehensive esophageal squamous cell carcinoma therapy: A case report. World J Clin Cases 2020; 8(19): 4550-4557 [PMID: 33083417 DOI: 10.12998/wjcc.v8.i19.4550]
Corresponding Author of This Article
Xiao-Feng He, MD, Chief Doctor, Professor, Division of Vascular and Interventional Radiology, Department of General Surgery, Nanfang Hospital, Southern Medical University, No. 1838 Guangzhou Avenue North, Guangzhou 510515, Guangdong Province, China. ozonetherapy@126.com
Research Domain of This Article
Gastroenterology & Hepatology
Article-Type of This Article
Case Report
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Clin Cases. Oct 6, 2020; 8(19): 4550-4557 Published online Oct 6, 2020. doi: 10.12998/wjcc.v8.i19.4550
Application of ozonated water for treatment of gastro-thoracic fistula after comprehensive esophageal squamous cell carcinoma therapy: A case report
De-Di Wu, Ke-Nan Hao, Xiao-Jing Chen, Xin-Min Li, Xiao-Feng He
De-Di Wu, Ke-Nan Hao, Xiao-Jing Chen, Xin-Min Li, Xiao-Feng He, Division of Vascular and Interventional Radiology, Department of General Surgery, Nanfang Hospital, Southern Medical University, Guangzhou 510515, Guangdong Province, China
Author contributions: Wu DD wrote the paper and collected the patient’s clinical data; Hao KN and Chen XJ administrated and followed the patient; Li XM performed the operation and approved the publication of the paper; He XF made critical revisions to the paper and designed the operation.
Supported byFoundation of President of Nanfang Hospital, Southern Medical University.
Informed consent statement: Informed consent was obtained from the patient.
Conflict-of-interest statement: There are no conflicts of interest to disclose.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: Xiao-Feng He, MD, Chief Doctor, Professor, Division of Vascular and Interventional Radiology, Department of General Surgery, Nanfang Hospital, Southern Medical University, No. 1838 Guangzhou Avenue North, Guangzhou 510515, Guangdong Province, China. ozonetherapy@126.com
Received: May 9, 2020 Peer-review started: May 9, 2020 First decision: May 15, 2020 Revised: May 28, 2020 Accepted: August 25, 2020 Article in press: August 25, 2020 Published online: October 6, 2020 Processing time: 141 Days and 13.2 Hours
Abstract
BACKGROUND
Gastro-thoracic fistula is a serious complication after radical surgery for esophageal cancer, and a conservative approach or endoscopic intervention is commonly applied to treat most cases.
CASE SUMMARY
Here we describe the case of a patient with a gastro-thoracic fistula which could not be closed during gastroscopy after receiving postoperative radiotherapy, together with severe multiple drug-resistant bacterial infection and chest wall fistula. The abscess was drained and local irrigation applied with ozonated water, together with oral ozonated water, which achieved a good effect and highlighted a new way to cure fistula in such patients.
CONCLUSION
Patients with gastro-thoracic fistula that cannot be closed and severe infection can be treated by drainage and flushing with ozonated water.
Core Tip: We report a patient whose gastro-thoracic fistula could not be closed surgically following radiotherapy, and who also presented with severe multiple drug-resistance bacterial infection and chest wall fistula. The patient was successfully treated by draining the abscess and applying local irrigation, as well as administering ozonated water orally. This case demonstrates that adequate local drainage and anti-infection treatment can be used to cure patients with severe infection and gastro-thoracic fistula which cannot be closed under endoscopy. As a supplement to conventional therapy, treatment using local irrigation with ozonated water to control infection can heal patients with this condition.
