Case Report
Copyright ©The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Feb 26, 2019; 7(4): 516-524
Published online Feb 26, 2019. doi: 10.12998/wjcc.v7.i4.516
Long-term follow-up of a patient with venlafaxine-induced diurnal bruxism treated with an occlusal splint: A case report
Jia-Min Chen, Ying Yan
Jia-Min Chen, Ying Yan, Department of Prosthodontics, Guanghua School of Stomatology, Hospital of Stomatology, Sun Yat-sen University, Guangdong Provincial Key Laboratory of Stomatology, Guangzhou 510055, Guangdong Province, China
Author contributions: Yan Y and Chen JM examined the patient and collected the clinical data; Chen JM wrote the paper; Yan Y edited the manuscript and approved the final version.
Informed consent statement: Informed consent was obtained from the patient for publication of this report and any accompanying images and videos.
Conflict-of-interest statement: All authors declare no conflict of interest for this article.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: Ying Yan, MSc, Associate Professor, Chief Doctor, Department of Prosthodontics, Guanghua School of Stomatology, Hospital of Stomatology, Sun Yat-sen University, Guangdong Provincial Key Laboratory of Stomatology, No. 56, West Linyuan Road, Guangzhou 510055, Guangdong Province, China. yanying2@mail.sysu.edu.cn
Telephone: +86-136-6073-2785 Fax: +86-020-83822807
Received: November 14, 2018
Peer-review started: November 14, 2018
First decision: December 22, 2018
Revised: January 8, 2019
Accepted: January 26, 2019
Article in press: January 26, 2019
Published online: February 26, 2019
Processing time: 104 Days and 0.7 Hours
Abstract
BACKGROUND

Bruxism is a jaw-muscle activity characterized by the clenching or grinding of teeth. It can be divided into nocturnal bruxism and diurnal bruxism (DB). DB secondary to antidepressants is rare and refractory. Reports associated with antidepressant-induced DB are mostly anecdotal without long-term follow-up. The effect of drug intervention on antidepressant-induced DB is still contested. We herein report the first case of successful treatment of venlafaxine-induced DB with an occlusal splint.

CASE SUMMARY

This case report describes detailed 7-year follow-up of a patient with venlafaxine-induced DB treated with an occlusal splint. The patient who complained about involuntary daytime tooth grinding after taking venlafaxine for a period of 4 mo and was diagnosed with venlafaxine-induced DB. Subsequently, an occlusal splint with modified bilateral buccal-pterygoid pads was used to treat his tooth grinding and to protect the dental structures from tooth wearing. The patient reported remission of symptoms after several months of treatment. His grinding activity was gradually and stably controlled after 2 years, with an almost complete recovery from DB after 6 years.

CONCLUSION

The maxillary buccal-pterygoid splint can be used as a noninvasive approach to treat venlafaxine-induced DB.

Keywords: Occlusal splint; Venlafaxine; Diurnal bruxism; Tooth grinding; Movement disorders; Treatment; Case report

Core tip: Secondary diurnal bruxism (DB) is rare and refractory. The existing literature associated with antidepressant-induced DB mostly consists of anecdotal reports without long-term follow-up. Therapeutic effects of drug intervention are still unclear. This case is the first to describe successful treatment of venlafaxine-induced DB with an occlusal splint.