Hui CC, Zhang X, Sun JR, Deng DT. Primary hyperparathyroidism in a woman with multiple tumors: A case report. World J Clin Cases 2019; 7(19): 3132-3137 [PMID: 31624765 DOI: 10.12998/wjcc.v7.i19.3132]
Corresponding Author of This Article
Da-Tong Deng, PhD, Associate Professor, Chief Physician, Department of Endocrinology, The First Affiliated Hospital of Anhui Medical University, 218 Jixi Road, Hefei 230022, Anhui Province, China. dengdayong@ahmu.edu.cn
Research Domain of This Article
Medicine, Research & Experimental
Article-Type of This Article
Case Report
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Clin Cases. Oct 6, 2019; 7(19): 3132-3137 Published online Oct 6, 2019. doi: 10.12998/wjcc.v7.i19.3132
Primary hyperparathyroidism in a woman with multiple tumors: A case report
Can-Can Hui, Xue Zhang, Jian-Ran Sun, Da-Tong Deng
Can-Can Hui, Xue Zhang, Da-Tong Deng, Department of Endocrinology, The First Affiliated Hospital of Anhui Medical University, Hefei 230022, Anhui Province, China
Jian-Ran Sun, Department of Endocrinology, The First Affiliated Hospital of USTC Anhui Provincial Hospital, Hefei 230001, Anhui Province, China
Author contributions: Deng DT designed the report; Hui CC and Zhang X collected the data; Hui CC, Zhang X, and Sun JR wrote the paper; All authors read and approved the final manuscript.
Informed consent statement: Informed written consent was obtained from the patient for publication of this report and any accompanying images.
Conflict-of-interest statement: The authors declare that they have no conflict of interest.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: Da-Tong Deng, PhD, Associate Professor, Chief Physician, Department of Endocrinology, The First Affiliated Hospital of Anhui Medical University, 218 Jixi Road, Hefei 230022, Anhui Province, China. dengdayong@ahmu.edu.cn
Telephone: +86-551-62922069 Fax: +86-551-62922160
Received: March 25, 2019 Peer-review started: March 26, 2019 First decision: May 31, 2019 Revised: June 25, 2019 Accepted: July 3, 2019 Article in press: July 3, 2019 Published online: October 6, 2019 Processing time: 189 Days and 1.5 Hours
Abstract
BACKGROUND
Parathyroid adenoma (PTA) is known as an adenomatous hyperparathyroidism syndrome. At earlier times, the major symptoms of this disease included high blood calcium and low phosphorus. PTA is a benign neuroendocrine neoplasm. We have reviewed the literature and found that it is rare for patients with hyperparathyroidism to have benign tumors with multiple organs at the same time. This report describes a patient with a PTA and four nonfunctional adenomas.
CASE SUMMARY
We report a case of primary hyperparathyroidism in a 39-year-old woman with multiple organ tumors. The patient was admitted to hospital because of hypercalcemia. Laboratory, imaging, and histological examinations confirmed a left parathyroid neoplasm. Right thyroid adenoma was discovered during hospitalization. She had a medical history of uterine fibroids, right benign mammary gland tumor, and meningioma. The patient recovered after surgical and conservative treatments.
CONCLUSION
Primary hyperparathyroidism with multiple organ tumors is uncommon, and further studies should be conducted to determine if there is genetic heterogeneity.
Core tip: Simultaneous occurrence of multiple tumors is rare. This article reports a patient who was admitted to hospital with hypercalcemia and finally diagnosed with a parathyroid adenoma via surgical pathology. The patient also had uterine fibroids, benign mammary gland tumor, and meningioma. After diagnosis, these tumors were all removed.
