Published online Oct 6, 2019. doi: 10.12998/wjcc.v7.i19.3126
Peer-review started: March 15, 2019
First decision: July 30, 2019
Revised: August 20, 2019
Accepted: August 25, 2019
Article in press: August 26, 2019
Published online: October 6, 2019
Clear cell sarcoma (CCS) of soft tissue is a rare malignant soft tissue sarcoma usually reported to locate at distal end of extremities and rarely at trunk. Herein, we report a case of CCS in pleural cavity.
A 31-year-old male was admitted for an uncertain mass in left pleural cavity in routine physical examination without any symptoms. A VATS surgery was performed to remove the tumor. The pathological finding displayed a cystic mass with 6.5 cm at the longest diameter, dark red in section and cysts could be found locally. A strong expression of S-100, HMB45 and Vimentin was detected in immunohistochemical staining, which was inclined to the diagnosis of the CCS of soft tissue. The patient refused chemotherapy, radiotherapy and targeted therapy because of the personal financial situation. Follow-up computed tomography scans were done at the 90th postoperative day and the 180th postoperative day, and no obvious sign of recurrence was found till now.
CCS of soft tissue also can be found in pleural cavity although in an extremely rare incidence. Radical resection is useful to improve the prognosis.
Core tip: Clear cell sarcoma (CCS) is a rare malignant tumor of soft tissue usually arising from extremities. Now we reported a case of CCS located on the chest cavity, confirmed by the positive stain of HMB-45 and S-100 mark in immunohistochemistry. Radical resection of the tumor was performed and the short-term outcome was good.