Published online Sep 26, 2019. doi: 10.12998/wjcc.v7.i18.2888
Peer-review started: May 9, 2019
First decision: May 30, 2019
Revised: July 12, 2019
Accepted: July 27, 2019
Article in press: July 27, 2019
Published online: September 26, 2019
Processing time: 151 Days and 23.6 Hours
Takayasu arteritis is a rare but intractable chronic disease in young female patients. Percutaneous transluminal angioplasty of the involved renal arteries has been reported; however, few studies have reported the use of drug coated balloon angioplasty in the treatment of Takayasu arteritis. We aimed to demonstrate five young female patients who presented with a history of hypertension due to Takayasu arteritis.
From April 2017 to October 2018, five female patients were diagnosed with hypertension due to Takayasu arteritis by computed tomography angiography (CTA) and laboratory tests. Four patients had a complaint of headache with or without dizziness, and one patient showed no symptom. There was no significant family or past history of hypertension or kidney disease, and the physical examinations were almost normal on admission. We performed a treatment by drug coated balloon angioplasty. Blood pressure decreased dramatically in all patients after balloon angioplasty, and the patency of treated renal artery was demonstrated with CTA over 5 months after the angioplasty procedure.
Drug coated balloon angioplasty is safe and effective for renal artery stenosis due to Takayasu arteritis. A prospective study with a larger sample size is necessary to further demonstrate the effectiveness of the treatment.
Core tip: Percutaneous transluminal angioplasty of the involved renal arteries has been reported; however, few cases were treated by drug coated balloon angioplasty. We aimed to demonstrate five young ladies who presented with a history of hypertension due to Takayasu arteritis. Our data indicated that drug coated balloon angioplasty is safe and effective for renal artery stenosis due to Takayasu arteritis.