Case Report
Copyright ©The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Sep 6, 2019; 7(17): 2605-2610
Published online Sep 6, 2019. doi: 10.12998/wjcc.v7.i17.2605
Organ-associated pseudosarcomatous myofibroblastic proliferation with ossification in the lower pole of the kidney mimicking renal pelvic carcinoma: A case report
Tian-Yuan Zhai, Bin-Jie Luo, Zhan-Kui Jia, Zheng-Guo Zhang, Xiang Li, Hao Li, Jin-Jian Yang
Tian-Yuan Zhai, Bin-Jie Luo, Zhan-Kui Jia, Zheng-Guo Zhang, Xiang Li, Hao Li, Jin-Jian Yang, Department of Urology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, Henan Province, China
Author contributions: Zhai TY, Luo BJ and Yang JJ designed the report; Zhang ZG, Li X and Li H collected the patient’s clinical data; Zhai TY, Jia ZK and Yang JJ analyzed the data and wrote the paper.
Supported by the National Natural Science Foundation of China, No. 81570685.
Informed consent statement: The study participants provided informed written consent prior to their treatments and study enrollment.
Conflict-of-interest statement: All authors declare no conflict of interest related to this study or its publication.
CARE Checklist (2016) statement: The manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: Jin-Jian Yang, MD, MD, Professor, Surgeon, Department of Urology, The First Affiliated Hospital of Zhengzhou University, No. 1 Jianshe Road, Zhengzhou 450052, Henan Province, China. yangjinjian2011@163.com
Telephone: +86-370-67967227Fax: +86-370-67967227
Received: March 17, 2019
Peer-review started: March 18, 2019
First decision: July 30, 2019
Revised: August 4, 2019
Accepted: August 20, 2019
Article in press: August 20, 2019
Published online: September 6, 2019
Processing time: 173 Days and 22.8 Hours
Abstract
BACKGROUND

Organ-associated pseudosarcomatous myofibroblastic proliferation (PMP) is a very rare disorder. In the urogenital tract, PMP preferentially involves the urinary bladder; kidney involvement is rare. Here, we report a rare case of PMP with ossification in the lower pole of the kidney, which mimics urothelial carcinoma or an osteogenic tumor.

CASE SUMMARY

A Chinese man was admitted to our hospital due to intermittent hematuria for more than 1 mo. Enhanced renal computed tomography revealed a mass in the left renal pelvis and upper ureter. The preoperative clinical diagnosis was renal pelvic carcinoma, determined by imaging examination and biopsy. After a standard preparation for surgery, the patient underwent retroperitoneoscopic radical nephroureterectomy. The operative findings were an extensive renal tumor (6 cm × 4.5 cm × 4.5 cm) invading the lower pole of the kidney and upper ureter. The final pathological diagnosis was organ-associated PMP with ossification. After 6-mo follow-up, no recurrence or metastasis was found.

CONCLUSION

This case of PMP was unusual for its mimicking renal pelvic carcinoma in imaging examinations, making biopsy necessary.

Keywords: Pseudosarcomatous myofibroblastic proliferation; Kidney; Renal pelvic; Carcinoma; Case report

Core tip: Organ-associated pseudosarcomatous myofibroblastic proliferation (PMP) in the urinary bladder has been reported. However, it rarely occurs in the kidney and no previous case of renal PMP with ossification have been reported. In this case report, the preoperative clinical diagnosis of renal pelvic carcinoma was made by imaging examination and biopsy. Retroperitoneoscopic radical nephroureterectomy was performed, and the final pathological diagnosis was organ-associated PMP with ossification. This case may help us to better understand this disease with regards to the related clinical manifestations, laboratory examination, imaging and pathologic results.