Zhu MY, Sun LQ. Ulcerative colitis complicated with colonic necrosis, septic shock and venous thromboembolism: A case report. World J Clin Cases 2019; 7(16): 2360-2366 [PMID: 31531332 DOI: 10.12998/wjcc.v7.i16.2360]
Corresponding Author of This Article
Li-Qun Sun, MD, Adjunct Professor, Critical Care Unit, the Second Affiliated Hospital of Nanjing Medical University, No. 121 Jiangjiayuan Road, Gulou District, Nanjing 210011, Jiangsu Province, China. njuslq@163.com
Research Domain of This Article
Medicine, Research & Experimental
Article-Type of This Article
Case Report
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Clin Cases. Aug 26, 2019; 7(16): 2360-2366 Published online Aug 26, 2019. doi: 10.12998/wjcc.v7.i16.2360
Ulcerative colitis complicated with colonic necrosis, septic shock and venous thromboembolism: A case report
Ming-Yu Zhu, Li-Qun Sun
Ming-Yu Zhu, Li-Qun Sun, Critical Care Unit, the Second Affiliated Hospital of Nanjing Medical University, Nanjing 210011, Jiangsu Province, China
Author contributions: Zhu MY drafted the manuscript; Sun LQ revised the article critically; All authors read and approved the final manuscript.
Informed consent statement: Written informed consent was obtained from the patient for publication of this case report.
Conflict-of-interest statement: No potential conflicts of interest relevant to this article were reported.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: Li-Qun Sun, MD, Adjunct Professor, Critical Care Unit, the Second Affiliated Hospital of Nanjing Medical University, No. 121 Jiangjiayuan Road, Gulou District, Nanjing 210011, Jiangsu Province, China. njuslq@163.com
Telephone: +86-15005168556
Received: May 9, 2019 Peer-review started: May 10, 2019 First decision: June 12, 2019 Revised: June 19, 2019 Accepted: July 20, 2019 Article in press: July 20, 2019 Published online: August 26, 2019 Processing time: 109 Days and 12.8 Hours
Abstract
BACKGROUND
Severe total colonic necrosis, septic shock and venous thromboembolism secondary to ulcerative colitis (UC) are rare and life-threatening. No such severe complications have been reported in the literature.
CASE SUMMARY
We report a 36-year-old woman who developed total colonic necrosis and septic shock secondary to UC. The patient was treated with emergency surgery because computed tomography showed suspicious perforations. Persistent massive ascites occurred after operation and computed tomography angiography demonstrated portal vein, mesenteric vein and splenic vein thrombosis. The patient was discharged from hospital after active treatment.
CONCLUSION
Clinicians should pay attention to venous thrombosis, colonic necrosis and septic shock in UC patients. Close observation of surgical indications and timely surgical intervention are the key to reduce mortality and complications in UC.
Core tip: Severe total colonic necrosis, septic shock and venous thromboembolism are rare but life-threatening complications of ulcerative colitis. Possibility of colonic necrosis in ulcerative colitis should be considered and close observation of surgical indications and timely surgical intervention are the key to reduce mortality and complications in ulcerative colitis.
