Published online Aug 26, 2019. doi: 10.12998/wjcc.v7.i16.2341
Peer-review started: February 26, 2019
First decision: June 19, 2019
Revised: June 21, 2019
Accepted: July 20, 2019
Article in press: July 20,2019
Published online: August 26, 2019
Processing time: 183 Days and 12.5 Hours
Due to some similarities in the manifestations between central serous chorioretinopathy (CSC) and polypoidal choroidal vasculopathy (PCV), PCV may be misdiagnosed as CSC. More attention should be paid to distinguishing these two disorders.
A 52-year-old woman presented to our hospital with blurred vision in her left eye for approximately 1 wk. Anterior segment and intraocular pressure findings were normal in both eyes. Fundus photography of the left eye showed a seemingly normal adult oculus fundus without any obvious hard exudate or hemorrhage. Optical coherence tomography exhibited a hypo-reflective space beneath both the neurosensory retina and the pigment epithelium layer. The late phase of fluorescein angiography revealed increased leakage. The patient was initially diagnosed with CSC. At follow-up, however, the final diagnosis turned out to be PCV.
CSC and PCV are two different retinal entities. Lipid deposition and hemorrhage are the most important elements that lead to confusion between these two entities. Indocyanine green angiography should be performed to make a definitive diagnosis, especially in cases with suspected PCV.
Core tip: Polypoidal choroidal vasculopathy and central serous chorioretinopathy are different diseases. While relatively mature research has been done on central serous chorioretinopathy, there is no unified understanding of polypoidal choroidal vasculopathy. These two diseases have some common symptoms, which have been plaguing clinicians. This case report provides a good example for the differential diagnosis between them. It also provides an alternative treatment for the clinical treatment of polypoidal choroidal vasculopathy.