Zhou DK, Liu ZH, Gao BQ, Wang WL. Giant nonfunctional ectopic adrenocortical carcinoma on the anterior abdominal wall: A case report. World J Clin Cases 2019; 7(15): 2075-2080 [PMID: 31423440 DOI: 10.12998/wjcc.v7.i15.2075]
Corresponding Author of This Article
Wei-Lin Wang, MD, PhD, Doctor, Department of Hepatobiliary and Pancreatic Surgery, The Second Affiliated Hospital, School of Medicine, Zhejiang University, No.88 Jiefang Road, Hangzhou 310003, Zhejiang Provine, China. wam@zju.edu.cn
Research Domain of This Article
Oncology
Article-Type of This Article
Case Report
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Clin Cases. Aug 6, 2019; 7(15): 2075-2080 Published online Aug 6, 2019. doi: 10.12998/wjcc.v7.i15.2075
Giant nonfunctional ectopic adrenocortical carcinoma on the anterior abdominal wall: A case report
Dong-Kai Zhou, Zheng-Hao Liu, Bing-Qiang Gao, Wei-Lin Wang
Dong-Kai Zhou, Zheng-Hao Liu, Bing-Qiang Gao, Wei-Lin Wang, Department of Hepatobiliary and Pancreatic Surgery, The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou 310003, Zhejiang Province, China
Dong-Kai Zhou, Zheng-Hao Liu, Bing-Qiang Gao, Wei-Lin Wang, Key Laboratory of Precision Diagnosis and Treatment for Hepatobiliary and Pancreatic Tumor of Zhejiang Province, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou 310003, Zhejiang Province, China
Dong-Kai Zhou, Zheng-Hao Liu, Bing-Qiang Gao, Wei-Lin Wang, Clinical Research Center of Hepatobiliary and Pancreatic Diseases of Zhejiang Province, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou 310003, Zhejiang Province, China
Author contributions: Zhou DK wrote the manuscript; Liu ZH collected case data and prepared the photos; Gao BQ, and Wang WL proofread and revised the manuscript; all of the authors approved the final version to be published.
Supported byThe National Natural Science Foundation of China, No. 81572307 and No. 81773096.
Informed consent statement: Informed consent was obtained from the patient.
Conflict-of-interest statement: The authors declare that there is no conflict of interest related to this report.
CARE Checklist (2016) statement: Guidelines of the CARE Checklist (2016) have been adopted while writing this manuscript.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: Wei-Lin Wang, MD, PhD, Doctor, Department of Hepatobiliary and Pancreatic Surgery, The Second Affiliated Hospital, School of Medicine, Zhejiang University, No.88 Jiefang Road, Hangzhou 310003, Zhejiang Provine, China. wam@zju.edu.cn
Telephone: +86-571-87315003Fax: +86-571-87022776
Received: April 15, 2019 Peer-review started: April 15, 2019 First decision: May 31, 2019 Revised: June 28, 2019 Accepted: July 3, 2019 Article in press: July 3,2019 Published online: August 6, 2019 Processing time: 115 Days and 5.6 Hours
Abstract
BACKGROUND
Adrenocortical cancer (ACC) is an infrequent and often aggressive malignancy with a very poor prognosis. It can be classified as functional or nonfunctional. Nonfunctional ACC is hampered by the absence of specific signs or symptoms; only abdominal pain with or without incidental adrenal occupation is typically present.
CASE SUMMARY
We report a rare case of a patient with a 30 cm × 15 cm × 8 cm ectopic ACC on the anterior abdominal wall without organ adhesion. A 77-year-old male was admitted to our hospital because of a huge abdominal mass, which, by ultrasonography, had an unclear border with the liver. Computed tomography showed that the mass was not associated with any organ but was adherent to the anterior abdominal wall. The patient underwent tumor resection, and a postoperative pathology examination showed a neuroendocrine tumor, which was diagnosed as ACC. The patient was disease-free at the 9-mo follow up.
CONCLUSION
The anterior abdominal wall is a rare site of ACC growth.
Core tip: Aberrant adrenal tissue can be found anywhere, but typically in the testes, ovaries, spermatic cord, and kidneys. The most common site is retroperitoneal fat near the adrenal gland; the bilateral lungs, liver, spleen, pancreas, colon, duodenum, and ovary are less common. This is, to our knowledge, the first report of adrenocortical cancer on the anterior abdominal wall in the English-language literature.
