Case Report
Copyright ©The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Oct 6, 2018; 6(11): 447-454
Published online Oct 6, 2018. doi: 10.12998/wjcc.v6.i11.447
Balo’s concentric sclerosis in a patient with spontaneous remission based on magnetic resonance imaging: A case report and review of literature
Özgür Ertuğrul, Esra Çiçekçi, Mehmet Cudi Tuncer, Mehmet Ufuk Aluçlu
Özgür Ertuğrul, Department of Radiology, Memorial Hospital, Diyarbakır 21100, Turkey
Esra Çiçekçi, Department of Physiotherapy, University of Health Sciences, Gazi Yaşargil Education and Research Hospital, Diyarbakır 21100, Turkey
Mehmet Cudi Tuncer, Department of Anatomy, Faculty of Medicine, University of Dicle, Diyarbakır 21280, Turkey
Mehmet Ufuk Aluçlu, Department of Neurology, Faculty of Medicine, University of Dicle, Diyarbakır 21280, Turkey
Author contributions: Ertuğrul Ö, Aluçlu MU and Çiçekçi E examined patient and collected clinical data; Ertuğrul Ö performed and analyzed radiologic imaging data; Tuncer MC and Ertuğrul Ö wrote the paper; Tuncer MC, Aluçlu MU and Ertuğrul Ö edited the manuscript and had final approval.
Informed consent statement: Informed written consent was obtained from the patient prior to all procedures described in the report as well as for the use of the patient’s clinical information and images for published scientific works.
Conflict-of-interest statement: All of the authors report no relationships that could be construed as a conflict of interest.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Mehmet Cudi Tuncer, PhD, Full Professor, Department of Anatomy, Faculty of Medicine, University of Dicle, Fabrika Mahallesi, 760. sokak, Sunrise 2 Evleri, E Blok, Kat: 3, No: 9, Diyarbakır 21280, Turkey. drcudi@hotmail.com
Telephone: +90-412-2488001 Fax: +90-532-2744926
Received: May 18, 2018
Peer-review started: May 19, 2018
First decision: July 8, 2018
Revised: July 30, 2018
Accepted: August 6, 2018
Article in press: August 6, 2018
Published online: October 6, 2018
Processing time: 133 Days and 3.2 Hours
Abstract

Balo’s concentric sclerosis (BCS) is a rare monophasic demyelinating disease known as multiple sclerosis subtype and seen as a round lesion with variable hyper and hypo-detoxification layers. Characteristic appearance can be seen as “bulb eye” or “onion bulb”. The initial terminology for this neurological disorder was leukoencephalitis periaxialis concentrica; this is defined as a disease in which the white matter of the brain is destroyed in concentric layers in such a way as to leave the axial cylinders intact. This report presents a case of BCS with spontaneous healing of the patient and a mass lesion with concentric rings adjacent to the left lateral ventricle and the posterior portion of the corpus callosum with peripheral vasogenic edema. The neurological lesion of the patient was similar to the magnetic resonance imaging and clinical findings of the BCS.

Keywords: Balo’s concentric sclerosis; Multiple sclerosis; Demyelinating; Magnetic resonance imaging; Diffusion-weighted imaging

Core tip: This case report demonstrates that Balo’s concentric sclerosis (BCS) a patient with a mass lesion containing concentric rings, BCS diagnosis was reported by magnetic resonance imaging. As supported in previously reported clinical trials, BCS is not always a fatal disease and supports the definition that it may be a self-limiting disease.