Published online Nov 16, 2017. doi: 10.12998/wjcc.v5.i11.403
Peer-review started: July 26, 2017
First decision: August 16, 2017
Revised: August 25, 2017
Accepted: September 12, 2017
Article in press: September 13, 2017
Published online: November 16, 2017
Cervical inlet patch (CIP), also referred to as esophageal heterotopic gastric mucosa, is regarded as the residue of columnar epithelium of the embryonic esophagus. Narrow band imaging increases the detection rate of CIP. Herein, we present a 55-year-old man with symptomatic circumferential inlet patch. He exhibited globus and dysphagia, and esophagogastroduodenoscopy found cir-cumferential CIP, where im-munohistochemistry revealed the existence of pro-ton pumps (H+, K+-ATPase). His throat symptoms were relieved by acid suppressive therapy with pump inhibitors. This case indicated that CIP should be considered as a differential diagnosis for the cause of globus symptoms in rare cases.
Core tip: Cervical inlet patch (CIP) is the esophageal heterotopic gastric mucosa in the cervical esophagus. We present a 55-year-old man exhibiting circumferential CIP with globus and dysphagia. Proton pump inhibitors relived these throat symptoms. Immunohistochemistry revealed existence of proton pumps in the CIP lesion. The throat symptoms were suggested to be related with CIP and acid secretion.