Copyright
©The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Feb 16, 2016; 4(2): 56-59
Published online Feb 16, 2016. doi: 10.12998/wjcc.v4.i2.56
Published online Feb 16, 2016. doi: 10.12998/wjcc.v4.i2.56
Black esophagus syndrome associated with diabetic ketoacidosis
Riccardo Rigolon, Irene Fossà, Giovanni Targher, Section of Endocrinology, Diabetes and Metabolism, Department of Medicine, University and Azienda Ospedaliera Universitaria Integrata of Verona, 37126 Verona, Italy
Luca Rodella, Emergency Endoscopy Unit, Azienda Ospedaliera Universitaria Integrata of Verona, 37126 Verona, Italy
Author contributions: All authors contributed to the acquisition of data, writing, and revision of the manuscript.
Institutional review board statement: The study was reviewed and approved by the local Institutional Review Board (Comitato etico per la sperimentazione clinica delle Province di Verona e Rovigo).
Informed consent statement: The patient involved in this study gave his informed written consent prior to study enrollment, authorizing the use and disclosure of his protected health information.
Conflict-of-interest statement: All the authors of the article have no conflicts of interest to disclose.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Giovanni Targher, Professor, Section of Endocrinology, Diabetes and Metabolism, Department of Medicine, University and Azienda Ospedaliera Universitaria Integrata of Verona, Piazzale Aristide Stefani, 37126 Verona, Italy. giovanni.targher@univr.it
Telephone: +39-45-8123749 Fax: +39-45-8027314
Received: August 27, 2015
Peer-review started: August 31, 2015
First decision: October 14, 2015
Revised: November 12, 2015
Accepted: December 3, 2015
Article in press: December 4, 2015
Published online: February 16, 2016
Processing time: 152 Days and 12.2 Hours
Peer-review started: August 31, 2015
First decision: October 14, 2015
Revised: November 12, 2015
Accepted: December 3, 2015
Article in press: December 4, 2015
Published online: February 16, 2016
Processing time: 152 Days and 12.2 Hours
Abstract
Acute esophageal necrosis, also known as “black esophagus syndrome”, is a rare acute esophageal disease that is often associated with vomiting and upper gastrointestinal haemorrhage. At present, little is known regarding the pathogenesis of this disease. We present the case of a 50-year-old white male patient with diabetic ketoacidosis suffering from acute esophageal necrosis with nausea and vomiting but without any clinical signs of upper gastrointestinal bleeding.
Core tip: The aetiology and pathogenesis of the so-called black esophagus syndrome are unclear. This case report supports a possible link between the occurrence of diabetic ketoacidosis and the black esophagus syndrome.