Editorial
Copyright ©The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Dec 16, 2016; 4(12): 385-389
Published online Dec 16, 2016. doi: 10.12998/wjcc.v4.i12.385
Primary splenic lymphoma: Current diagnostic trends
Sachin B Ingle, Chitra R Hinge (Ingle)
Sachin B Ingle, Department of Pathology, MIMSR Medical College, Latur, Maharashtra 4132512, India
Chitra R Hinge (Ingle), Department of Physiology, MIMSR Medical College, Latur, Maharashtra 4132512, India
Author contributions: Ingle SB prepared the first draft of the manuscript; Hinge (Ingle) CR critically revised the manuscript, added intellectual content and approved the final draft of the manuscript.
Conflict-of-interest statement: All the authors hereby declare that they have no any conflicts of interests.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Sachin B Ingle, Professor, Department of Pathology, MIMSR Medical College, Ambajogai Road, vishwanathpuram, Latur, Maharashtra 4132512, India. dr.sachiningle@gmail.com
Telephone: +91-2382-227424 Fax: +91-2382-228939
Received: March 13, 2016
Peer-review started: March 14, 2016
First decision: April 20, 2016
Revised: October 9, 2016
Accepted: October 22, 2016
Article in press: October 24, 2016
Published online: December 16, 2016
Processing time: 268 Days and 23.8 Hours
Abstract

The primary splenic lymphoma is extremely uncommon, can present with grave complications like hypersplenism and splenic rupture. In view of vague clinical presentation, it is difficult to arrive at the diagnosis. In such circumstances, histopathological diagnosis is very important. A precise diagnosis can only be made on histopathology and confirmed on immunohistochemistry.Emergency splenectomy is preferred as an effective therapeutic and diagnostic tool in cases with giant splenomegaly. Core biopsy is usually not advised due to a high risk of post-core biopsy complications in view of its high vascularity and fragility. Aim behind highlighting the topic is to specify that core biopsy/ fine needle aspiration cytology can be used as an effective diagnostic tool to arrive at correct diagnosis to prevent untoward complications related to disease and treatment. Anticoagulation therapy is vital after splenectomy to avoid portal splenic vein thrombosis.

Keywords: Splenic lymphoma; Biopsy; Immunohistochemistry

Core tip: Primary splenic lymphoma is a rare entity, has vague clinical presentation and can present with grave complications like hypersplenism and splenic rupture. In such circumstances, core biopsy/fine needle aspiration cytology can hit the correct pathological diagnosis. Emergency splenectomy is an effective therapeutic and diagnostic tool in cases with massive splenomegaly with features of hypersplenism.