Published online Dec 16, 2016. doi: 10.12998/wjcc.v4.i12.385
Peer-review started: March 14, 2016
First decision: April 20, 2016
Revised: October 9, 2016
Accepted: October 22, 2016
Article in press: October 24, 2016
Published online: December 16, 2016
The primary splenic lymphoma is extremely uncommon, can present with grave complications like hypersplenism and splenic rupture. In view of vague clinical presentation, it is difficult to arrive at the diagnosis. In such circumstances, histopathological diagnosis is very important. A precise diagnosis can only be made on histopathology and confirmed on immunohistochemistry.Emergency splenectomy is preferred as an effective therapeutic and diagnostic tool in cases with giant splenomegaly. Core biopsy is usually not advised due to a high risk of post-core biopsy complications in view of its high vascularity and fragility. Aim behind highlighting the topic is to specify that core biopsy/ fine needle aspiration cytology can be used as an effective diagnostic tool to arrive at correct diagnosis to prevent untoward complications related to disease and treatment. Anticoagulation therapy is vital after splenectomy to avoid portal splenic vein thrombosis.
Core tip: Primary splenic lymphoma is a rare entity, has vague clinical presentation and can present with grave complications like hypersplenism and splenic rupture. In such circumstances, core biopsy/fine needle aspiration cytology can hit the correct pathological diagnosis. Emergency splenectomy is an effective therapeutic and diagnostic tool in cases with massive splenomegaly with features of hypersplenism.