Virgilio E, Mercantini P, Cavallini M. Is endoscopic resection a correct treatment for atypical gastrointestinal lipomas? World J Clin Cases 2016; 4(1): 30-32 [PMID: 26798629 DOI: 10.12998/wjcc.v4.i1.30]
Corresponding Author of This Article
Dr. Edoardo Virgilio, Medical and Surgical Sciences and Translational Medicine, Faculty of Medicine and Psychology “Sapienza”, St. Andrea Hospital, via di Grottarossa 1035-39, 00189 Rome, Italy. aresedo1992@yahoo.it
Research Domain of This Article
Oncology
Article-Type of This Article
Letters To The Editor
Open-Access Policy of This Article
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World J Clin Cases. Jan 16, 2016; 4(1): 30-32 Published online Jan 16, 2016. doi: 10.12998/wjcc.v4.i1.30
Is endoscopic resection a correct treatment for atypical gastrointestinal lipomas?
Edoardo Virgilio, Paolo Mercantini, Marco Cavallini
Edoardo Virgilio, Paolo Mercantini, Marco Cavallini, Medical and Surgical Sciences and Translational Medicine, Faculty of Medicine and Psychology “Sapienza”, St. Andrea Hospital, 00189 Rome, Italy
Author contributions: Virgilio E and Mercantini P wrote this letter; Cavallini M revised the letter.
Conflict-of-interest statement: Nothing to declare.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Dr. Edoardo Virgilio, Medical and Surgical Sciences and Translational Medicine, Faculty of Medicine and Psychology “Sapienza”, St. Andrea Hospital, via di Grottarossa 1035-39, 00189 Rome, Italy. aresedo1992@yahoo.it
Telephone: +39-06-33775989 Fax: +39-06-33775322
Received: May 6, 2015 Peer-review started: May 8, 2015 First decision: July 26, 2015 Revised: August 26, 2015 Accepted: November 3, 2015 Article in press: November 4, 2015 Published online: January 16, 2016 Processing time: 253 Days and 8.3 Hours
Abstract
We would like offering our experience about a very rare and underestimated type of gastrointestinal lipoma, which is the lipoma with precancerous or frankly malignant features of the mucosal epithelium, the so-called atypical lipoma. So far, only few cases have been described in the world literature. Recently, we grappled with what we think the first case of atypical colonic lipoma presenting with adenocarcinomatous transformation of the overlying epithelium, as discussed in more detail below. We propose a new definition and classification for this kind of lesions and discuss about their diagnosis, treatment and prognosis.
Core tip: We report a case of atypical lipoma of the colon with malignant transformation of the mucosal epithelium. No standardized treatment exists. Endoscopic resection with close follow-up is probably the most appropriate management to pursue for this kind of lesions.
