Case Report
Copyright ©The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Aug 16, 2015; 3(8): 751-756
Published online Aug 16, 2015. doi: 10.12998/wjcc.v3.i8.751
Combined surgical-orthodontic rehabilitation of cleidocranial dysplasia: 5 years follow-up
Emre Çimen, Ömür Dereci, Ayşegül Mine Tüzüner-Öncül, Duygu Yazıcıoğlu, Erhan Özdiler, Aslı Şenol, Nejat Bora Sayan
Emre Çimen, Private Practice, 34890 Istanbul, Turkey
Ömür Dereci, Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Eskişehir Osmangazi University, 26480 Eskişehir, Turkey
Ayşegül Mine Tüzüner-Öncül, Nejat Bora Sayan, Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Ankara University, 06500 Ankara, Turkey
Duygu Yazıcıoğlu, Private Practice, 06500 Ankara, Turkey
Erhan Özdiler, Aslı Şenol, Department of Orthodontics, Faculty of Dentistry, Ankara University, 06500 Ankara, Turkey
Author contributions: Çimen E, Tüzüner-Öncül AM, Özdiler E and Sayan NB designed the research; Çimen E, Tüzüner-Öncül AM, Yazıcıoglu D and Sayan NB performed the surgery; Özdiler E and Şenol A performed orthodontic treatment; Çimen E, Dereci Ö, Özdiler E and Şenol A analyzed the data; Dereci Ö and Çimen E wrote the paper.
Institutional review board statement: The name of our instutional review board is ‘Clinical Research Ethical Board of Eskişehir Osmangazi University, Faculty of Medicine.’ This study is a case report with a long follow-up. Our Ethical board does not accept case reports due to there is no need for ethical approval for case reports. Therefore, we did not apply for instutional ethical board for approval.
Informed consent statement: Patient presented in this study gave his informed consent prior to study inclusion.
Conflict-of-interest statement: All authors declare that there is no conflict of interest.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See:
Correspondence to: Dr. Ömür Dereci, Asisstant Professor, Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Eskişehir Osmangazi University, Meşelik Campus, 26480 Eskişehir, Turkey.
Telephone: +90-222-2391303 Fax: +90-222-2391273
Received: April 6, 2015
Peer-review started: April 8, 2015
First decision: April 27, 2015
Revised: June 3, 2015
Accepted: June 18, 2015
Article in press: July 15, 2015
Published online: August 16, 2015

Cleidocranial dysplasia (CD) is an autosomal dominant syndrome which is characterized by several skeletal malformations such as non-closed fontanelles, skeletal abnormalities of the maxilla and mandible and absence of clavicles. Mid-facial hypoplasia and mandibular prognathism are mostly seen jaw abnormalities in CD. In this study, the combined orthodontic-surgical treatment of a patient with CD with class III malocclusion and multiple unerupted primary and deciduous teeth is presented.

Keywords: Cleidocranial dysplasia, Marie-Sainton syndrome, Forced eruption, Prognathism, Orthodontic extrusion

Core tip: Cleidocranial dysplasia is a syndromic disease with distinct craniofacial and maxillofacial manifestations. The satisfactory treatment of dental and skeletal deformities in this disease can only be possible with combined orthodontic-surgical approach.