Published online May 16, 2015. doi: 10.12998/wjcc.v3.i5.470
Peer-review started: December 24, 2014
First decision: January 20, 2015
Revised: January 24, 2015
Accepted: February 9, 2015
Article in press: February 11, 2015
Published online: May 16, 2015
Processing time: 137 Days and 3.7 Hours
Congenital pulmonary airway malformation (CPAM), previously known as congenital cystic adenomatoid malformation is a congenital disorder of the lung similar to bronchopulmonary sequestration. In CPAM, usually an entire lobe of lung is replaced by a non-working cystic piece of abnormal lung tissue. This abnormal tissue will never function as normal lung tissue. The underlying cause for CPAM is not known. It occurs in approximately 1 in every 30000 pregnancies. The association between CPAM and malignancy has been well documented. There is a small risk (0.7%) of malignant transformation within the cyst. So early diagnosis and surgical resection is important to prevent the grave complications. Herein, we are reporting two interesting cases of CPAM and one belonged to Type II and other belonged to Type III of Stocker’s classification.
Core tip: Congenital pulmonary airway malformation (CPAM) is a rare disease with various clinical presentations and having the risk of future malignant transformation. Early pulmonary resection for asymptomatic CPAM is required and recommended to make a definitive diagnosis and determine the prognosis of the disease.