Case Report
Copyright ©The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. May 16, 2015; 3(5): 470-473
Published online May 16, 2015. doi: 10.12998/wjcc.v3.i5.470
Congenital pulmonary airway malformation: A report of two cases
Saroj Bolde, Smita Pudale, Gopal Pandit, Kirti Ruikar, Sachin B Ingle
Saroj Bolde, Smita Pudale, Gopal Pandit, Kirti Ruikar, Department of Pathology Dr V.M. Govt Medical College, Solapur, Maharashtra 413003, India
Sachin B Ingle, Department of Pathology and Secretary Research and Development, MIMSR Medical College, Latur, Maharashtra 413531, India
Author contributions: Bolde S, Pudale S and Ruikar K prepared the manuscript; Pandit G and Ingle SB critically revised the intellectual content and gave final approval of manuscript.
Ethics approval: This case report is conducted in MIMSR Medical College, Latur, MAharashtra, India.
Informed consent: It is not need to disclose.
Conflict-of-interest: None to be declared.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Sachin B Ingle, Professor, Department of Pathology and Secretary Research and Development, MIMSR Medical College, Ambajogai Road, Vishwanathpuram, Latur, Maharashtra 413531, India. dr.sachiningle@gmail.com
Telephone: +91-2382-227424 Fax: +91-2382-22893
Received: December 22, 2014
Peer-review started: December 24, 2014
First decision: January 20, 2015
Revised: January 24, 2015
Accepted: February 9, 2015
Article in press: February 11, 2015
Published online: May 16, 2015
Processing time: 137 Days and 3.7 Hours
Abstract

Congenital pulmonary airway malformation (CPAM), previously known as congenital cystic adenomatoid malformation is a congenital disorder of the lung similar to bronchopulmonary sequestration. In CPAM, usually an entire lobe of lung is replaced by a non-working cystic piece of abnormal lung tissue. This abnormal tissue will never function as normal lung tissue. The underlying cause for CPAM is not known. It occurs in approximately 1 in every 30000 pregnancies. The association between CPAM and malignancy has been well documented. There is a small risk (0.7%) of malignant transformation within the cyst. So early diagnosis and surgical resection is important to prevent the grave complications. Herein, we are reporting two interesting cases of CPAM and one belonged to Type II and other belonged to Type III of Stocker’s classification.

Keywords: Congenital pulmonary airway malformation-Type II, Congenital pulmonary airway malformation-Type III, Surgical resection

Core tip: Congenital pulmonary airway malformation (CPAM) is a rare disease with various clinical presentations and having the risk of future malignant transformation. Early pulmonary resection for asymptomatic CPAM is required and recommended to make a definitive diagnosis and determine the prognosis of the disease.