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©The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Oct 16, 2015; 3(10): 861-863
Published online Oct 16, 2015. doi: 10.12998/wjcc.v3.i10.861
Published online Oct 16, 2015. doi: 10.12998/wjcc.v3.i10.861
Proliferative verrucous leukoplakia may initially mimic lichenoid reactions
Marcio Ajudarte Lopes, Patricia Feio, Alan Roger Santos-Silva, Pablo Agustin Vargas, Oral Diagnosis Department, Semiology and Oral Pathology, Piracicaba Dental School, State University of Campinas (UNICAMP), Piracicaba, Sao Paulo 13083-970, Brazil
Author contributions: Lopes MA designed the research and wrote the paper; Feio P wrote the paper; Santos-Silva AR and Vargas PA attended the patient and reviewed the paper.
Conflict-of-interest statement: The authors declare no conflict-of-interest.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Marcio Ajudarte Lopes, DDS, PhD, Oral Diagnosis Department, Semiology and Oral Pathology, Piracicaba Dental School, State University of Campinas (UNICAMP), Av. Limeira, 901, Bairro Areão, Piracicaba, Sao Paulo 13083-970, Brazil. malopes@fop.unicamp.br
Telephone: +55-19-21065320 Fax: + 55-19-21065218
Received: February 11, 2015
Peer-review started: February 12, 2015
First decision: May 13, 2015
Revised: June 29, 2015
Accepted: September 7, 2015
Article in press: September 8, 2015
Published online: October 16, 2015
Processing time: 246 Days and 21.6 Hours
Peer-review started: February 12, 2015
First decision: May 13, 2015
Revised: June 29, 2015
Accepted: September 7, 2015
Article in press: September 8, 2015
Published online: October 16, 2015
Processing time: 246 Days and 21.6 Hours
Abstract
Proliferative verrucous leukoplakia is an intriguing disease, which occurs particularly in women aged greater than 60 years, is not associated with tobacco and alcohol, and has a high risk of recurrence and malignant transformation. Although it is well known that the typical presentation is characterized by multifocal and verrucous white lesions, there is no description that its initial clinical presentation may simulate a lichenoid reaction.
Core tip: Although uncommon, it is important for the clinician to recognize the main features of proliferative verrucous leukoplakia in order to provide the correct diagnosis and appropriate management.