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World J Clin Cases. Sep 16, 2014; 2(9): 426-431
Published online Sep 16, 2014. doi: 10.12998/wjcc.v2.i9.426
Clinical usefulness and current problems of pancreatic duct stenting for preventing post-ERCP pancreatitis
Yuji Sakai, Toshio Tsuyuguchi, Osamu Yokosuka
Yuji Sakai, Toshio Tsuyuguchi, Osamu Yokosuka, Department of Gastroenterology and Nephrology, Graduate School of Medicine, Chiba University, Chiba 260-8677, Japan
Author contributions: Sakai Y wrote the paper; Tsuyuguchi T and Yokosuka O revised the manuscript.
Correspondence to: Yuji Sakai, MD, Department of Gastroenterology and Nephrology, Graduate School of Medicine, Chiba University, Inohana 1-8-1, Chuou-ku, Chiba 260-8670, Japan. sakai4754@yahoo.co.jp
Telephone: +81-43-2262083 Fax: +81-43-2262088
Received: April 16, 2014
Revised: May 21, 2014
Accepted: June 27, 2014
Published online: September 16, 2014
Abstract

Endoscopic retrograde cholangiopancreatography (ERCP) is an endoscopic procedure with high frequency of accidental symptoms, and particularly some patients who develop and aggravate pancreatitis due to the procedure may need treatment of surgery or die. Various attempts were performed so far to prevent post-ERCP pancreatitis, however, it is impossible to completely prevent pancreatitis at this time because there are various factors for occurrence of post-ERCP pancreatitis. One of the most frequent causes of post-ERCP pancreatitis is considered to be congestion of pancreatic juice associated with duodenal papilledema after examination or treatment. Recently it is often reported that use of a pancreatic duct stent may prevent occurrence of pancreatitis which occurs because of an increased inner pressure of the pancreatic duct caused by congestion of pancreatic juice associated with duodenal papilledema. However, there are some patients who develop pancreatitis even if treated with the pancreatic duct stent, thus further clarification of the pathology and advancement of the prophylactic method will be needed.

Keywords: Endoscopic retrograde cholangiopancreatography, Post-endoscopic retrograde cholangiopancreatography pancreatitis, Pancreatic duct stent, Pancreatic stenting

Core tip: There are some patients who can avoid occurrence of post-endoscopic retrograde cholangiopancreatography pancreatitis (ERCP) pancreatitis by pancreatic duct stenting. However, it is impossible to prevent all post-ERCP pancreatitides by pancreatic duct stenting, and further examination will be needed.