Case Report
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World J Clin Cases. Jul 16, 2014; 2(7): 311-315
Published online Jul 16, 2014. doi: 10.12998/wjcc.v2.i7.311
Diagnostic pitfall of sebaceous gland metaplasia of the esophagus
King-Wah Chiu, Cheng-Kun Wu, Long-Sheng Lu, Hock-Liew Eng, Shue-Shian Chiou
King-Wah Chiu, Cheng-Kun Wu, Long-Sheng Lu, Shue-Shian Chiou, Department of Internal Medicine, Division of Gastroenterology and Hepatology, Kaohsiung Chang Gung Memorial Hospital, and Chang Gung University, College of Medicine, Kaohsiung 83305, Taiwan
Hock-Liew Eng, Department of Pathology, Kaohsiung Chang Gung Memorial Hospital, and Chang Gung University, College of Medicine, Kaohsiung 83305, Taiwan
Author contributions: Chiu KW designed the report; Chiou SS was attending doctors for the patients; Eng HL performed pathological examinations; Wu CK and Lu LS were performed image diagnosis; Chiu KW and Chiou SS organized the report; and Chiu KW wrote paper.
Correspondence to: King-Wah Chiu, MD, Department of Internal Medicine, Division of Gastroenterology and Hepatology, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University, College of Medicine, 123, Ta-Pei Road, Niao-Sung District, Kaohsiung 83305, Taiwan. kwchiu@adm.cgmh.org.tw
Telephone: +886-7-73171238190 Fax: +886-7-7336856
Received: October 12, 2013
Revised: March 6, 2014
Accepted: May 16, 2014
Published online: July 16, 2014
Processing time: 280 Days and 23.5 Hours
Abstract

We investigated the sebaceous gland metaplasia (SGM) of the esophagus and clarified the evidence of misdiagnosis and its diagnosis pitfall. Cases of pathologically proven SGM were enrolled in the clinical analysis and reviewed description of endoscope. In the current study, we demonstrated that SGM is very rare esophageal condition with an incidence around 0.00465% and an occurrence rate of 0.41 per year. There were 57.1% of senior endoscopists identified 8 episodes of SGM. In contrast, 7.7% of junior endoscopists identified SGM in only 2 episodes. Moreover, we investigated the difference in endoscopic biopsy attempt rate between the senior and junior endoscopist (P = 0.0001). The senior endoscopists had more motivation to look for SGM than did junior endoscopists (P = 0.01). We concluded that SGM of the esophagus is rare condition that is easily and not recognized in endoscopy studies omitting pathological review.

Keywords: Esophagus; Sebaceous gland; Metaplasia; Endoscopy; Endoscopist

Core tip: Cases of pathologically proven sebaceous gland metaplasia (SGM) of the esophagus were enrolled in the clinical analysis and reviewed the description of endoscope. It is very rare esophageal condition with an incidence around 0.00465% and an occurrence rate of 0.41 per year. There are 57.1% of senior endoscopists identified 8 episodes of SGM and 7.7% of junior endoscopists identified SGM in only 2 episodes. The senior endoscopist had more motivation to look for SGM than did junior endoscopists. We concluded SGM of the esophagus is rare condition that is easily and not recognized in endoscopy studies omitting pathological review.