Editorial
Copyright ©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Jan 26, 2025; 13(3): 97737
Published online Jan 26, 2025. doi: 10.12998/wjcc.v13.i3.97737
Advancing healthcare through laboratory on a chip technology: Transforming microorganism identification and diagnostics
Carlos M Ardila
Carlos M Ardila, Department of Basic Sciences, Biomedical Stomatology Research Group, Universidad de Antioquia U de A, Medellín 0057, Colombia
Author contributions: Ardila CM performed the conceptualization, data curation, data analysis, manuscript writing, and revision of the manuscript; the author read and approved the final version of the manuscript to be published.
Conflict-of-interest statement: Author certifies that there is no conflict of interest related to the manuscript.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Carlos M Ardila, Doctor, MSc, PhD, Academic Research, Associate Professor, Department of Basic Sciences, Biomedical Stomatology Research Group, Universidad de Antioquia U de A, Calle 67 Nmero 53–108, Medellín 0057, Colombia. martin.ardila@udea.edu.co
Received: June 6, 2024
Revised: October 1, 2024
Accepted: October 22, 2024
Published online: January 26, 2025
Processing time: 158 Days and 17.3 Hours
Abstract

In a recent case report in the World Journal of Clinical Cases, emphasized the crucial role of rapidly and accurately identifying pathogens to optimize patient treatment outcomes. Laboratory-on-a-chip (LOC) technology has emerged as a transformative tool in health care, offering rapid, sensitive, and specific identification of microorganisms. This editorial provides a comprehensive overview of LOC technology, highlighting its principles, advantages, applications, challenges, and future directions. Success studies from the field have demonstrated the practical benefits of LOC devices in clinical diagnostics, epidemiology, and food safety. Comparative studies have underscored the superiority of LOC technology over traditional methods, showcasing improvements in speed, accuracy, and portability. The future integration of LOC with biosensors, artificial intelligence, and data analytics promises further innovation and expansion. This call to action emphasizes the importance of continued research, investment, and adoption to realize the full potential of LOC technology in improving healthcare outcomes worldwide.

Keywords: Laboratory-on-a-chip; Microorganism identification; Diagnostics; Point-of-care testing; Biosensors

Core Tip: Laboratory-on-a-chip (LOC) technology revolutionizes microorganism identification, offering rapid diagnostics with high sensitivity and portability. Integrating microfluidics, biosensors, and artificial intelligence, LOC devices enhance clinical decision-making, accelerate outbreak response, and enable personalized treatments. Overcoming technical challenges and regulatory hurdles, LOC promises transformative impact across healthcare, environmental monitoring, and food safety. Continued research, investment, and adoption are essential to realize its full potential in advancing global health outcomes.