Zheng WX, Liu LY. Urgent thrombolysis followed by percutaneous coronary intervention for the simultaneous acute cardio-cerebral ischemic attack: A case report. World J Clin Cases 2025; 13(21): 105816 [DOI: 10.12998/wjcc.v13.i21.105816]
Corresponding Author of This Article
Ling-Yu Liu, MD, Department of Traditional Chinese Medicine, The General Hospital of Western Theater Command, No. 270 Rongdu Avenue, Jinniu District, Chengdu 610036, Sichuan Province, China. 2317352371@qq.com
Research Domain of This Article
Cardiac & Cardiovascular Systems
Article-Type of This Article
Case Report
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Clin Cases. Jul 26, 2025; 13(21): 105816 Published online Jul 26, 2025. doi: 10.12998/wjcc.v13.i21.105816
Urgent thrombolysis followed by percutaneous coronary intervention for the simultaneous acute cardio-cerebral ischemic attack: A case report
Wen-Xue Zheng, Ling-Yu Liu
Wen-Xue Zheng, Section 1 of Cadre Wards, The General Hospital of Western Theater Command, Chengdu 610036, Sichuan Province, China
Ling-Yu Liu, Department of Traditional Chinese Medicine, The General Hospital of Western Theater Command, Chengdu 610036, Sichuan Province, China
Author contributions: Zheng WX collected data from the medical records, described the case histories as documented in the records, and prepared the initial draft of the manuscript; Liu LY reviewed and edited the manuscript; all authors have read and agreed to the published version of the manuscript.
Informed consent statement: Written informed consent was obtained from the patient for publication of this manuscript.
Conflict-of-interest statement: The authors declare no financial relationships or conflicts of interest.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Ling-Yu Liu, MD, Department of Traditional Chinese Medicine, The General Hospital of Western Theater Command, No. 270 Rongdu Avenue, Jinniu District, Chengdu 610036, Sichuan Province, China. 2317352371@qq.com
Received: February 8, 2025 Revised: March 4, 2025 Accepted: March 21, 2025 Published online: July 26, 2025 Processing time: 78 Days and 23.3 Hours
Abstract
BACKGROUND
Simultaneous acute ischemic stroke (AIS) and myocardial infarction (cardiocerebral ischemic attack) have rarely been reported in the literature. Currently, no clear evidence-based guidelines or clinical trials exist to determine the optimal therapeutic strategy for these patients.
CASE SUMMARY
We present the case of a 27-year-old Chinese man who simultaneously experienced acute concomitant cerebrocardiac infarction (CCI) and painless ST-elevation myocardial infarction. The patient was successfully treated with elective percutaneous coronary intervention (PCI) after receiving urgent systemic thrombolysis at the standard dose for AIS.
CONCLUSION
Urgent thrombolysis followed by elective PCI was an appropriate strategy for the management of simultaneous CCI.
Core Tip: Simultaneous acute ischemic stroke and acute myocardial infarction [cardio-cerebral ischemic attack, concomitant cerebrocardiac infarction (CCI)] has been rarely reported in the literature. There are currently no clear evidence-based guidelines or clinical trials in order to address an optimal therapeutic strategy for patients with this dilemma. This report aimed to highlight the urgent thrombolysis followed elective percutaneous coronary intervention, that showed to be relatively an appropriate strategy for management of simultaneous CCI.
