Chen LQ, Wu CY, Wu SJ, Ye K. Laparoscopic surgical approaches for various locations of gastrointestinal stromal tumours. World J Clin Cases 2025; 13(21): 105559 [DOI: 10.12998/wjcc.v13.i21.105559]
Corresponding Author of This Article
Kai Ye, MD, PhD, Associate Professor, Chief Physician, Department of Colorectal Surgery, The Second Affiliated Hospital of Fujian Medical University, No. 950 Donghai Street, Quanzhou 362000, Fujian Province, China. medwcy@163.com
Research Domain of This Article
Gastroenterology & Hepatology
Article-Type of This Article
Minireviews
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Clin Cases. Jul 26, 2025; 13(21): 105559 Published online Jul 26, 2025. doi: 10.12998/wjcc.v13.i21.105559
Laparoscopic surgical approaches for various locations of gastrointestinal stromal tumours
Li-Quan Chen, Chu-Ying Wu, Si-Jia Wu, Kai Ye
Li-Quan Chen, Chu-Ying Wu, Kai Ye, Department of Colorectal Surgery, The Second Affiliated Hospital of Fujian Medical University, Quanzhou 362000, Fujian Province, China
Si-Jia Wu, Department of Gynecology and Obstetrics, The Second Affiliated Hospital of Fujian Medical University, Quanzhou 362000, Fujian Province, China
Co-first authors: Li-Quan Chen and Chu-Ying Wu.
Author contributions: Chen LQ contributed to original draft preparation, writing, and review; Wu CY contributed to writing, review, and editing; Wu SJ contributed to writing, review; Ye K contributed to conceptualization, supervision, and funding acquisition; all authors have read and agreed to the published version of the manuscript. Chen LQ and Wu CY contributed equally to the study.
Supported by Quanzhou Science and Technology Plan Projects, No. 2024NY033; and Key Clinical Specialty Discipline Construction Program of Fujian (Fujian Health Medicine and Politics), No. [2022]884.
Conflict-of-interest statement: All authors report no conflicts of interest.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Kai Ye, MD, PhD, Associate Professor, Chief Physician, Department of Colorectal Surgery, The Second Affiliated Hospital of Fujian Medical University, No. 950 Donghai Street, Quanzhou 362000, Fujian Province, China. medwcy@163.com
Received: January 27, 2025 Revised: March 18, 2025 Accepted: April 1, 2025 Published online: July 26, 2025 Processing time: 90 Days and 22.2 Hours
Abstract
Gastrointestinal stromal tumours (GISTs) are tumours that originate from mesenchymal tissue, are predominantly located in the stomach, and typically do not metastasize to the lymph nodes. Surgical intervention remains the primary treatment modality for GISTs. Historically, open surgery was the predominant approach; however, advancements in medical technology have led to laparoscopic surgery becoming the standard practice. Compared with traditional open surgical techniques, laparoscopic surgery is less invasive and facilitates more rapid postoperative recovery. Given that GISTs can arise at any location within the gastrointestinal tract, the specific surgical methods employed vary according to both the tumour's anatomical site and its growth characteristics. The aim of this review is to examine laparoscopic surgical strategies for managing GISTs across different regions of the gastrointestinal tract by synthesizing recent research trends and relevant evidence-based medical literature.
Core Tip: Laparoscopic surgery has emerged as the primary treatment modality for gastrointestinal stromal tumours (GISTs). The surgical approach should be tailored to the specific anatomical location and growth characteristics of the tumour. This study provides a comprehensive review of the laparoscopic surgical techniques employed for treating GISTs located in various regions of the gastrointestinal tract, drawing upon recent research findings and evidence-based medical literature.
