Nong XF, Cao X, Tan XL, Jing LY, Liu H. Percheron syndrome with memory impairment as chief manifestation: A case report. World J Clin Cases 2025; 13(13): 98937 [DOI: 10.12998/wjcc.v13.i13.98937]
Corresponding Author of This Article
Hao Liu, MD, Department of Cardiology, The Seventh Affiliated Hospital of Southern Medical University, No. 28 Desheng Road, Foshan 528200, Guangdong Province, China. liuhao819@126.com
Research Domain of This Article
Neuroimaging
Article-Type of This Article
Case Report
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Clin Cases. May 6, 2025; 13(13): 98937 Published online May 6, 2025. doi: 10.12998/wjcc.v13.i13.98937
Percheron syndrome with memory impairment as chief manifestation: A case report
Xi-Feng Nong, Xiao Cao, Xing-Lin Tan, Li-Yan Jing, Hao Liu
Xi-Feng Nong, Xiao Cao, Xing-Lin Tan, Li-Yan Jing, Department of Neurology, The Seventh Affiliated Hospital of Southern Medical University, Foshan 528200, Guangdong Province, China
Hao Liu, Department of Cardiology, The Seventh Affiliated Hospital of Southern Medical University, Foshan 528200, Guangdong Province, China
Author contributions: Nong XF, Cao X, Tan XL, and Jing LY designed the study; Nong XF and Liu H performed the research; Nong XF drafted the manuscript; and all authors have read and approved the final manuscript.
Supported by the Young Innovative Talents Fund of Guangdong Colleges and Universities, No. 2023KQNCX013.
Informed consent statement: All study participants, or their legal guardian, provided informed written consent prior to study enrollment.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Hao Liu, MD, Department of Cardiology, The Seventh Affiliated Hospital of Southern Medical University, No. 28 Desheng Road, Foshan 528200, Guangdong Province, China. liuhao819@126.com
Received: July 9, 2024 Revised: November 14, 2024 Accepted: December 27, 2024 Published online: May 6, 2025 Processing time: 186 Days and 0.1 Hours
Abstract
BACKGROUND
Percheron acute artery occlusion is a rare type of acute cerebral infarction.
CASE SUMMARY
An elderly male presented with sudden-onset near-memory and sensory impairments for 5 days. Upon admission, based on symptoms, signs, magnetic resonance imaging, and computed tomography findings, a diagnosis of Percheron syndrome was made. Subsequently, anti-platelet therapy, lipid-lowering treatment, cerebral circulation enhancement (such as the administration of calcium channel blockers to improve cerebral blood flow), and neurotrophic support (such as the use of drugs like citicoline to protect nerve cells) were immediately implemented, along with additional symptomatic treatments. The patient’s symptoms were alleviated, following which he was discharged.
CONCLUSION
The diagnosis of acute occlusion of the Percheron artery requires rich clinical expertise and accurate imaging tools. Timely intervention and effective follow-up hold significant implications for optimizing patient recovery.
Core Tip: This article is a case report of Percheron syndrome, a special acute cerebral infarction. For patients with sudden memory decline, the disease was diagnosed by careful neurological localization and auxiliary examinations of magnetic resonance imaging and contrast-enhanced computed tomography. Eventually, the patient improved and was discharged after conservative treatment. It is hoped that this case can heighten neurologists’ vigilance against Percheron syndrome.
