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World J Clin Cases. Apr 16, 2025; 13(11): 99748
Published online Apr 16, 2025. doi: 10.12998/wjcc.v13.i11.99748
Nipah virus: Preventing the next outbreak
Satvik Tyagi, Shalini Upadhyay, Tanisha Bharara, Sanjeev Sahai
Satvik Tyagi, Shalini Upadhyay, Sanjeev Sahai, Department of Microbiology, Amar Shaheed Jodha Singh Ataiya Thakur Dariyao Singh Medical College, Fatehpur 212601, Uttar Pradesh, India
Tanisha Bharara, Department of Microbiology, North Delhi Municipal Corporation Medical College and Hindu Rao Hospital, New Delhi 110007, India
Author contributions: Tyagi S, Upadhyay S, Bharara T, Sahai S contributed to this paper; Upadhyay S and Bharara T designed the overall concept and outline of the manuscript; Sahai S contributed to the discussion and design of the manuscript; Tyagi S and Upadhyay S contributed to the writing, illustrations, and review of literature; Bharara T and Upadhyay S contributed to edit the manuscript.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Tanisha Bharara, MBBS, MD, Assistant Professor, Department of Microbiology, North Delhi Municipal Corporation Medical College and Hindu Rao Hospital, Malka Ganj, Kamla Nehru Bridge, New Delhi 110007, India. tanishabharara.med@gmail.com
Received: July 29, 2024
Revised: November 11, 2024
Accepted: December 11, 2024
Published online: April 16, 2025
Processing time: 149 Days and 20.5 Hours
Abstract

Nipah is a deadly viral infection which has come to the news highlight recently, due to its fresh onslaught in Southern India. As the world continues to recover from coronavirus disease 2019, the World Health Organization has identified a list of high-priority pathogens with the potential to cause future pandemics. Among them is the Nipah virus (NiV), which poses a significant threat. Even a small outbreak could trigger widespread panic among the public. The emergence and re-emergence of NiV among other zoonotic infections is a stern reminder of the importance of One health concept.

Keywords: Encephalitis; Pandemic potential; Re-emergence; One health; Zoonosis

Core Tip: Nipah is a bat borne, zoonotic virus that is notorious to cause serious human outbreaks. The recent coronavirus disease 2019 (COVID-19) pandemic has shed light on the One Health approach and is a stark reminder of the indolent threat of emerging and re-emerging zoonotic infections. Lessons learned from the global COVID-19 pandemic can be applied to managing infections limited to regional outbreaks, such as Nipah, to help prevent recurrent re-emergences. Further studies on Nipah virus, disease development, diagnostic modalities, and treatment options, are need of the hour.