Published online Feb 26, 2024. doi: 10.12998/wjcc.v12.i6.1104
Peer-review started: December 7, 2023
First decision: December 17, 2023
Revised: December 18, 2023
Accepted: January 31, 2024
Article in press: January 31, 2024
Published online: February 26, 2024
Acute pancreatitis is a rare extrapulmonary manifestation of coronavirus disease 2019 (COVID-19) but its full correlation with COVID-19 infection remains un
To identify acute pancreatitis’ occurrence, clinical presentation and outcomes in a cohort of kidney transplant recipients with acute COVID-19.
A retrospective observational single-centre cohort study from a transplant centre in Croatia for all adult renal transplant recipients with a functioning kidney allo
Four hundred and eight out of 1432 (28.49%) patients who received a renal allo
Although rare, acute pancreatitis may complicate the course of acute COVID-19 in kidney transplant recipients. The mechanism of injury to the pancreas and its correlation with the severity of the COVID-19 infection in kidney transplant recipients warrants further research.
Core Tip: The attention to the effect of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus on pancreatic tissue has been arising. It is hypothesized that the SARS-CoV-2 virus can directly affect pancreatic tissue via angiotensin-converting enzyme 2 receptors which are heavily expressed in pancreatic cells. Our single-centre retrospective study aimed to identify the occurrence of acute pancreatitis, clinical presentation and outcomes in a cohort of kidney transplant recipients with acute coronavirus disease 2019 (COVID-19) between March 2020 and August 2022. 28.49% of transplant recipients developed COVID-19 disease and only 0.3% developed acute pancreatitis during the acute COVID-19 presenting with abdominal pain and elevated pancreatic enzymes with no imaging features. The mechanism of injury to the pancreas and its correlation with the severity of the COVID-19 infection in kidney transplant recipients warrants further research.