Dilek ÖF, Sevim KZ, Dilek ON. Acellular dermal matrices in reconstructive surgery; history, current implications and future perspectives for surgeons. World J Clin Cases 2024; 12(35): 6791-6807 [DOI: 10.12998/wjcc.v12.i35.6791]
Corresponding Author of This Article
Ömer F Dilek, MD, Assistant Professor, Department of Plastic, Reconstructive and Aesthetic Surgery, University of Health Sciences, Şişli Hamidiye Etfal Training and Research Hospital, 34396, Sarıyer, İstanbul 34396, Türkiye. ofdilek@gmail.com
Research Domain of This Article
Surgery
Article-Type of This Article
Review
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Clin Cases. Dec 16, 2024; 12(35): 6791-6807 Published online Dec 16, 2024. doi: 10.12998/wjcc.v12.i35.6791
Acellular dermal matrices in reconstructive surgery; history, current implications and future perspectives for surgeons
Osman N Dilek, Kamuran Z Sevim, Ömer F Dilek
Ömer F Dilek, Department of Plastic, Reconstructive and Aesthetic Surgery, University of Health Sciences, Şişli Hamidiye Etfal Training and Research Hospital, İstanbul 34396, Türkiye
Kamuran Z Sevim, Department of Plastic and Reconstructive Surgery, University of Health Sciences, Şişli Hamidiye Etfal Training and Research Hospital, İstanbul 34396, Türkiye
Osman N Dilek, Department of Surgery, İzmir Katip Celebi University, School of Medicine, İzmir 35150, Türkiye
Author contributions: Dilek ÖF, Sevim KZ, and Dilek ON contributed to this paper; Dilek ÖF designed the overall concept and outline of the manuscript; Sevim KZ contributed to the literature review and design of the manuscript; Dilek ÖF and Sevim KZ contributed to the writing, and editing the manuscript, table, and references; Dilek ON made supervision and final proofing in all aspects.
Conflict-of-interest statement: All authors declare that they have no conflict of interest.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Ömer F Dilek, MD, Assistant Professor, Department of Plastic, Reconstructive and Aesthetic Surgery, University of Health Sciences, Şişli Hamidiye Etfal Training and Research Hospital, 34396, Sarıyer, İstanbul 34396, Türkiye. ofdilek@gmail.com
Received: May 27, 2024 Revised: October 3, 2024 Accepted: October 15, 2024 Published online: December 16, 2024 Processing time: 149 Days and 22.4 Hours
Abstract
Large-scale defects of body in the reconstructive surgical practice, and the helplessness of their repair with autologous tissues, have been an important factor in the development of artificial biological products for the temporary, definitive, or staged repair of these defects. A major advance in the field of plastic and other reconstructive surgery in this regard has been the introduction and successful use of acellular dermal matrices (ADMs). In recent years, not only the type of tissue from which ADMs are produced, product range, diversity and areas of use have increased, but their use in reconstructive fields, especially in post oncologic breast surgery, has become highly regarded and this has favored ADMs to be a potential cornerstone in specific and well-defined surgical fields in future. It is essential that reconstructive surgeons become familiar with some of the ADM’s as well as the advantages and limitations to their use. This review not only provides basic science and clinical evidence of the current use of ADMs in wide range of surgical fields but also targets to keep them as an important backdrop in the armamentarium of reconstructive surgeons. Brief considerations of possible future directions for ADMs are also conducted in the end.
Core Tip: The use of acellular dermal matrix in parotid tumor surgery can reduce the incidence of Frey syndrome, especially when the diameter of the surgically removed parotid tissue is greater than 4 cm. This review not only provides basic science and clinical evidence of the current use of acellular dermal matrices in wide range of surgical fields but also targets to keep them as an important backdrop in the armamentarium of reconstructive surgeons.
