Xu L, Chen SS, Yang C, Cao HJ. Successful endoscopic treatment of superficial esophageal cancer in a patient with esophageal variceal bleeding: A case report. World J Clin Cases 2024; 12(27): 6105-6110 [PMID: 39328865 DOI: 10.12998/wjcc.v12.i27.6105]
Corresponding Author of This Article
Shan-Shan Chen, MD, Attending Doctor, Department of Gastrointestinal Medicine, The First Affiliated Hospital of Zhejiang Chinese Medical University, No. 9 Street, Qiantang District, Hangzhou 310018, Zhejiang Province, China. chenshanshan198848@126.com
Research Domain of This Article
Gastroenterology & Hepatology
Article-Type of This Article
Case Report
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Clin Cases. Sep 26, 2024; 12(27): 6105-6110 Published online Sep 26, 2024. doi: 10.12998/wjcc.v12.i27.6105
Successful endoscopic treatment of superficial esophageal cancer in a patient with esophageal variceal bleeding: A case report
Li Xu, Shan-Shan Chen, Chao Yang, Hai-Jun Cao
Li Xu, Shan-Shan Chen, Department of Gastrointestinal Medicine, The First Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou 310018, Zhejiang Province, China
Chao Yang, Department of Orthopaedics, The 903rd Hospital of the PLA of China, Hangzhou 310000, Zhejiang Province, China
Hai-Jun Cao, Department of Gastroenterology, The First Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou 310018, Zhejiang Province, China
Author contributions: Xu L reviewed the literature and contributed to manuscript drafting; Yang C collected all the data related to the case report; Chen SS and Cao HJ revised the manuscript for important intellectual content; and all the authors read and approved the final manuscript.
Supported bythe Zhejiang Medicine and Health Science and Technology Project, No. 2022RC217.
Informed consent statement: Written informed consent was obtained from the patient for the publication of this case report.
Conflict-of-interest statement: The authors declare that they have no conflict of interest to disclose.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Shan-Shan Chen, MD, Attending Doctor, Department of Gastrointestinal Medicine, The First Affiliated Hospital of Zhejiang Chinese Medical University, No. 9 Street, Qiantang District, Hangzhou 310018, Zhejiang Province, China. chenshanshan198848@126.com
Received: January 27, 2024 Revised: June 21, 2024 Accepted: July 10, 2024 Published online: September 26, 2024 Processing time: 185 Days and 13.4 Hours
Abstract
BACKGROUND
The coexistence of esophageal variceal bleeding and superficial esophageal cancer (SEC) is relatively rare in clinical practice. Moreover, there have been few reports of SEC overlying esophageal varices (EVs). Herein, we report our successful use of endoscopic submucosal dissection (ESD), esophageal solitary venous dilatation (ESVD), and endoscopic injection sclerotherapy (EIS) to treat a 75-year-old man who was diagnosed with SEC coexisting with esophageal variceal bleeding.
CASE SUMMARY
A 75-year-old man was admitted to the hospital due to black stool for 4 days. The patient had a history of liver cancer, cirrhosis, and portal hypertension. Endoscopic examination revealed esophageal and gastric varicose veins, as well as esophageal carcinoma in situ. We first treated esophageal variceal bleeding by ESVD and EIS. One week later, ESD treatment was done, and the complete resection of early esophageal cancer was successfully completed via endoscopy. There were no postoperative complications, such as bleeding, infection, or perforation.
CONCLUSION
The sequential treatment of ESVD, EIS, and ESD is an effective method for treating EVs with early esophageal cancer.
Core Tip: Esophageal varices (EVs) with bleeding and superficial esophageal cancer (SEC) are two different diseases. Their coexistence is rare in clinical practice. Endoscopic submucosal dissection (ESD) for SEC with EVs is one of the most challenging endoscopic procedures due to the high risk of bleeding and fibrosis caused by prior treatment. We report on a 75-year-old man with “black stool”. He had a history of cirrhosis and portal hypertension. After esophageal solitary venous dilatation and endoscopic injection sclerotherapy, ESD was successfully performed without significant complications, and the SEC was treated by R0 resection. This method may become the mainstream treatment for EVs with SEC.
