Retrospective Cohort Study
Copyright ©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Sep 16, 2024; 12(26): 5885-5892
Published online Sep 16, 2024. doi: 10.12998/wjcc.v12.i26.5885
Risk factors and clinical significance of posterior slip of the proximal vertebral body after lower lumbar fusion
Jia-Jun Zhu, Yi Wang, Jun Zheng, Sheng-Yang Du, Lei Cao, Yu-Ming Yang, Qing-Xi Zhang, Ding-Ding Xie
Jia-Jun Zhu, Yi Wang, Jun Zheng, Sheng-Yang Du, Lei Cao, Yu-Ming Yang, Qing-Xi Zhang, Ding-Ding Xie, Department of Spinal Surgery, Xuzhou First People’s Hospital, Xuzhou 221112, Jiangsu Province, China
Jia-Jun Zhu, Yi Wang, Jun Zheng, Sheng-Yang Du, Lei Cao, Yu-Ming Yang, Qing-Xi Zhang, Ding-Ding Xie, Department of Spinal Surgery, The Affiliated Xuzhou Municipal Hospital of Xuzhou Medical University, Xuzhou 221112, Jiangsu Province, China
Jia-Jun Zhu, Yi Wang, Jun Zheng, Sheng-Yang Du, Lei Cao, Yu-Ming Yang, Qing-Xi Zhang, Ding-Ding Xie, Department of Spinal Surgery, The Affiliated Hospital of China University of Mining and Technology, Xuzhou 221112, Jiangsu Province, China
Co-first authors: Jia-Jun Zhu and Yi Wang.
Author contributions: Xie DD, Zhu JJ, Zheng J, Cao L and Du SY designed the research study; Xie DD, Zhu JJ, Wang Y, Yang YM and Zhang QX performed the research; Zhu JJ and Wang Y contributed analytic tools; Xie DD, Zhu JJ and Wang Y analyzed the data and wrote the manuscript. All authors have read and approve the final manuscript.
Supported by The Youth Medicine Technology Innovation Project of Xuzhou Health Commission, No. XWKYHT20200026.
Institutional review board statement: The study was reviewed and approved by the Xuzhou First people’s Hospital Institutional Review Board.
Informed consent statement: All study participants, or their legal guardian, provided informed written consent prior to study enrollment.
Conflict-of-interest statement: All the authors declare no conflicts of interest.
Data sharing statement: Technical appendix, statistical code, and dataset available from the corresponding author at dd2225@126.com.
STROBE statement: The authors have read the STROBE Statement-checklist of items, and the manuscript was prepared and revised according to the STROBE Statement-checklist of items.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Ding-Ding Xie, MM, Attending Doctor, Department of Spinal Surgery, Xuzhou First People’s Hospital, No. 269 Daxue Road, Xuzhou 221112, Jiangsu Province, China. dd2225@126.com
Received: March 18, 2024
Revised: June 7, 2024
Accepted: June 25, 2024
Published online: September 16, 2024
Processing time: 126 Days and 18.3 Hours
Abstract
BACKGROUND

Adjacent segment disease (ASD) after fusion surgery is frequently manifests as a cranial segment instability, disc herniation, spinal canal stenosis, spondylolisthesis or retrolisthesis. The risk factors and mechanisms of ASD have been widely discussed but never clearly defined.

AIM

To investigate the risk factors and clinical significance of retrograde movement of the proximal vertebral body after lower lumbar fusion.

METHODS

This was a retrospective analysis of the clinical data of patients who underwent transforaminal lumbar interbody fusion surgery between September 2015 and July 2021 and who were followed up for more than 2 years. Ninety-one patients with degenerative lumbar diseases were included (22 males and 69 females), with an average age of 52.3 years (40-73 years). According to whether there was retrograde movement of the adjacent vertebral body on postoperative X-rays, the patients were divided into retrograde and nonretrograde groups. The sagittal parameters of the spine and pelvis were evaluated before surgery, after surgery, and at the final follow-up. At the same time, the Oswestry Disability Index (ODI) and Visual Analogue Scale (VAS) were used to evaluate the patients’ quality of life.

RESULTS

Nineteen patients (20.9%) who experienced retrograde movement of proximal adjacent segments were included in this study. The pelvic incidence (PI) of the patients in the retrograde group were significantly higher than those of the patients in the nonretrograde group before surgery, after surgery and at the final follow-up (P < 0.05). There was no significant difference in lumbar lordosis (LL) between the two groups before the operation, but LL in the retrograde group was significantly greater than that in the nonretrograde group postoperatively and at the final follow-up. No significant differences were detected in terms of the |PI–LL|, and there was no significant difference in the preoperative lordosis distribution index (LDI) between the two groups. The LDIs of the retrograde group were 68.1% ± 11.5% and 67.2% ± 11.9%, respectively, which were significantly lower than those of the nonretrograde group (75.7% ± 10.4% and 74.3% ± 9.4%, respectively) (P < 0.05). Moreover, the patients in the retrograde group had a greater incidence of a LDI < 50% than those in the nonretrograde group (P < 0.05). There were no significant differences in the ODI or VAS scores between the two groups before the operation, but the ODI and VAS scores in the retrograde group were significantly worse than those in the nonretrograde group after the operation and at the last follow-up, (P < 0.05).

CONCLUSION

The incidence of posterior slippage after lower lumbar fusion was approximately 20.9%. The risk factors are related to a higher PI and distribution of lumbar lordosis. When a patient has a high PI and insufficient reconstruction of the lower lumbar spine, adjacent segment compensation via posterior vertebral body slippage is one of the factors that significantly affects surgical outcomes.

Keywords: Adjacent segment disease; Posterior vertebral slip; Sagittal alignment of spine-pelvis; Lower lumbar fusion; Quality of life

Core Tip: Sagittal alignment of the spine and pelvis was assessed for patients with or without retrograde of the adjacent vertebra body on postoperative X-rays. We concluded that the risk factors of the posterior slip of the proximal vertebra body after lower lumbar fusion are related to a higher pelvic incidence (PI) and distribution of lumbar lordosis. When a patient has a high PI and insufficient reconstruction of the lower lumbar spine, adjacent segment compensation via posterior vertebra body slippage is one of the factors that significantly affects surgical outcomes.