Sun YH, Lu SS, Fang Y, Xiong Z, Sun QY, Huang J. Rare primary colonic T cell lymphoma with curative resection by endoscopic submucosal dissection: A case report. World J Clin Cases 2024; 12(22): 5229-5235 [DOI: 10.12998/wjcc.v12.i22.5229]
Corresponding Author of This Article
Jin Huang, MD, PhD, Chief Doctor, Professor, Gastroenterology Center, The Affiliated Changzhou Second People's Hospital of Nanjing Medical University, No. 68 Gehu Road, Wujin District, Changzhou 213000, Jiangsu Province, China. hj042153@hotmail.com
Research Domain of This Article
Gastroenterology & Hepatology
Article-Type of This Article
Case Report
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Yu-Hui Sun, Qiu-Yue Sun, Nanjing Medical University, The Affiliated Changzhou Second People's Hospital of Nanjing Medical University, Changzhou 213000, Jiangsu Province, China
Shuang-Shuang Lu, Jin Huang, Gastroenterology Center, The Affiliated Changzhou Second People's Hospital of Nanjing Medical University, Changzhou 213000, Jiangsu Province, China
Ying Fang, Zhe Xiong, Dalian Medical University, The Affiliated Changzhou Second People's Hospital of Nanjing Medical University, Changzhou 213000, Jiangsu Province, China
Author contributions: Huang J performed a considerable amount of work on colonoscopy, endoscopic submucosal dissection, and postoperative follow-up; Sun YH wrote the manuscript, revised the manuscript, collected the data, and is the guarantor of the article; Lu SS, Xiong Z, Fang Y, and Sun QY revised the manuscript for intellectual content; The manuscript was written through the contributions of all the authors; All authors have approved the final version of the manuscript.
Informed consent statement: Informed written consent was obtained from the patient for publication of this report and any accompanying images.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Jin Huang, MD, PhD, Chief Doctor, Professor, Gastroenterology Center, The Affiliated Changzhou Second People's Hospital of Nanjing Medical University, No. 68 Gehu Road, Wujin District, Changzhou 213000, Jiangsu Province, China. hj042153@hotmail.com
Received: April 14, 2024 Revised: May 23, 2024 Accepted: June 7, 2024 Published online: August 6, 2024 Processing time: 78 Days and 18.4 Hours
Abstract
BACKGROUND
The gastrointestinal tract is a well-known extranodal site of lymphoma. B-cell lymphoma is the most common type, while T-cell lymphoma is uncommon. Primary gastrointestinal lymphoma mainly occurs in the stomach and small intestine, and the colon is less frequently involved, especially in females.
CASE SUMMARY
A 45-year-old woman was admitted to our hospital for physical examination. Gastroenteroscopy revealed a visible pedunculated polyp in the transverse colon, for which endoscopic submucosal dissection (ESD) was performed. Pathology suggested highly active proliferation of T lymphocytes with atypical hyperplasia.
CONCLUSION
A middle-aged female patient was found to have colonic T-cell lymphoma by endoscopy. The lesion was successfully removed by ESD, and the surgical margin was negative. It is essential to raise awareness of colonic T-cell lymphoma and choose the appropriate treatment.
Core Tip: Primary colonic lymphoma is a very rare malignant tumor for which there is no standard treatment. We report a case of primary colonic T-cell lymphoma similar to a pedunculated polyp, and endoscopic submucosal dissection (ESD) was performed for diagnosis and treatment. ESD could be a feasible and economical choice for the treatment of colonic lymphomas. With the popularization of the concept of minimal invasiveness and the continuous development of minimally invasive technology, endoscopic surgery will have high application value for early gastrointestinal lesions.
