Wang T, Jiang J, Guo LL, Chen X, Chen EB. Heterotopic pancreas in the gallbladder: A case report. World J Clin Cases 2024; 12(22): 5140-5144 [DOI: 10.12998/wjcc.v12.i22.5140]
Corresponding Author of This Article
Er-Bao Chen, MD, Doctor, Department of Hepatobiliary and Pancreatic Surgery, Peking University Shenzhen Hospital, No. 1120 Lianhua Road, Futian District, Shenzhen 518036, Guangdong Province, China. ebchen17@fudan.edu.cn
Research Domain of This Article
Gastroenterology & Hepatology
Article-Type of This Article
Case Report
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Ting Wang, Xu Chen, Er-Bao Chen, Department of Hepatobiliary and Pancreatic Surgery, Peking University Shenzhen Hospital, Shenzhen 518036, Guangdong Province, China
Jing Jiang, Department of Pathology, Peking University Shenzhen Hospital, Shenzhen 518036, Guangdong Province, China
Ling-Ling Guo, Department of Radiation Oncology, Peking University Shenzhen Hospital, Shenzhen 518036, Guangdong Province, China
Author contributions: Wang T and Jiang J drafted and revised the manuscript; Guo LL and Chen X generated figures; Chen EB drafted, revised and approved the final manuscript; All authors have read and approved the final manuscript.
Supported bythe National Natural Science Foundation of China, No. 82303446.
Informed consent statement: Written informed consent has been obtained from the patient for publication of this case report.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Er-Bao Chen, MD, Doctor, Department of Hepatobiliary and Pancreatic Surgery, Peking University Shenzhen Hospital, No. 1120 Lianhua Road, Futian District, Shenzhen 518036, Guangdong Province, China. ebchen17@fudan.edu.cn
Received: February 22, 2024 Revised: May 19, 2024 Accepted: June 5, 2024 Published online: August 6, 2024 Processing time: 130 Days and 22.7 Hours
Abstract
BACKGROUND
Heterotopic pancreas (HP) refers to pancreatic tissue located in areas with no vascular or anatomical connection to the pancreas. HP occurs mostly in the stomach, duodenum, and colon, and rarely in the gallbladder.
CASE SUMMARY
A 57-year-old woman was referred to our hospital complaining of right upper quadrant discomfort for 3 years. An abdominal computed tomography scan revealed adenomyomatosis with a thickened fundus of the gallbladder. The patient underwent a laparoscopic cholecystectomy, and pathological examination unexpectedly showed heterotopic pancreatic tissue in the gallbladder. The patient had a favorable recovery and was discharged on postoperative day 3. She did not report any symptoms or complications at the 6-mo postoperative follow-up. Pathologists should pay close attention to such pancreatic tissue and carefully examine it for dysplasia or malignancy.
CONCLUSION
This case provides more information about HP in the gallbladder, a rare occurrence.
Core Tip: In this study, we report a rare case of heterotopic pancreatic tissue in the gallbladder. The patient was initially diagnosed with adenomyomatosis through a computed tomography scan. She underwent a laparoscopic cholecystectomy, and pathological examination revealed heterotopic pancreatic tissue in the gallbladder. Although the malignant transformation of heterotopic pancreatic tissue is rare, pathologists should be aware of this condition and carefully examine the tissue for dysplasia or malignancy.
