Liu M, Chen YT, Wang GL, Wu XM. Risk factors for intensive-care-unit-acquired weakness. World J Clin Cases 2024; 12(21): 4853-4855 [DOI: 10.12998/wjcc.v12.i21.4853]
Corresponding Author of This Article
Xue-Mei Wu, MD, PhD, Doctor, Department of Pediatric Neurology, First Hospital of Jilin University, No. 1 Xinmin Street, Changchun 130021, Jilin Province, China. xmwu@jlu.edu.cn
Research Domain of This Article
Clinical Neurology
Article-Type of This Article
Letter to the Editor
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Clin Cases. Jul 26, 2024; 12(21): 4853-4855 Published online Jul 26, 2024. doi: 10.12998/wjcc.v12.i21.4853
Risk factors for intensive-care-unit-acquired weakness
Ming Liu, Yu-Tong Chen, Guang-Liang Wang, Xue-Mei Wu
Ming Liu, Yu-Tong Chen, Xue-Mei Wu, Department of Pediatric Neurology, First Hospital of Jilin University, Changchun 130021, Jilin Province, China
Guang-Liang Wang, Department of Cardiology, Guo Jin Hospital, Changchun 130000, Jilin Province, China
Xue-Mei Wu, Jilin Provincial Key Laboratory of Pediatric Neurology, Jilin Provincial Key Laboratory, Changchun 130000, Jilin Province, China
Author contributions: Liu M wrote the manuscript; Chen YT and Wang GL collected related information; Wu XM revised the manuscript; All authors have read and approve the final manuscript.
Supported bythe National Natural Science Foundation of China, No. 81801284; and the National Natural Science Foundation of Jilin Province, No. YDZJ202201ZYTS091.
Conflict-of-interest statement: All the authors declare that they have no conflict of interest.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Xue-Mei Wu, MD, PhD, Doctor, Department of Pediatric Neurology, First Hospital of Jilin University, No. 1 Xinmin Street, Changchun 130021, Jilin Province, China. xmwu@jlu.edu.cn
Received: February 26, 2024 Revised: May 8, 2024 Accepted: June 5, 2024 Published online: July 26, 2024 Processing time: 125 Days and 5.6 Hours
Abstract
Wang et al reported 1063 cases from the initial 14 d of intensive care unit (ICU) stay, and analyzed relevant data such as age, comorbidities, recent dosages, vapor pressure dosages, duration of mechanical ventilation, length of ICU stay, and rehabilitation therapy, which are closely related to ICU-acquired weakness (ICU-AW). It is suggested that the length of ICU stay and the duration of mechanical ventilation are the main factors. ICU-AW is the most common neuromuscular injury in the ICU, which affects clinical progression and outcomes of patients. This manuscript helps to improve the early recognition of ICU-AW, thereby reducing mortality and improving prognosis.
Core Tip: The manuscript is helpful to improve the diagnosis and treatment of intensive-care-unit-acquired weakness (ICU-AW). ICU-AW is the most common neuromuscular injury that affects the clinical progression and outcomes of ICU patients. Multiple mechanisms are involved in the occurrence and development of ICU-AW; however, the relationship between these mechanisms still needs to be elucidated in order to reduce mortality and improve prognosis.
