Xu ZY, Pan Y, Ye WJ, Liu JL, Wu XJ, Tang CL. Primary hepatic lymphoma presenting as pyogenic liver abscess: A case report. World J Clin Cases 2024; 12(21): 4742-4747 [DOI: 10.12998/wjcc.v12.i21.4742]
Corresponding Author of This Article
Cui-Lan Tang, PhD, Professor, Department of Infectious Diseases, The Second Affiliated Hospital of Zhejiang University School of Medicine, No. 88 Jiefang Road, Hangzhou 318000, Zhejiang Province, China. 2317001@zju.edu.cn
Research Domain of This Article
Infectious Diseases
Article-Type of This Article
Case Report
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Zhi-Yang Xu, Ying Pan, Wen-Jing Ye, Jin-Liang Liu, Xue-Jie Wu, Cui-Lan Tang, Department of Infectious Diseases, The Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou 318000, Zhejiang Province, China
Author contributions: Pan Y and Ye WJ treated the patient; Wu XJ and Liu JL supervised this project and the manuscript writing; Xu ZY drafted the manuscript; Tang CL revised the article; all authors have reviewed and approved the final manuscript.
Informed consent statement: This study received approval from the Ethics Commission for Clinical Research of the Second Affiliated Hospital of Zhejiang University School of Medicine. Informed consent was waived due to the retrospective nature of the study.
Conflict-of-interest statement: The authors have no conflicts of interest to declare.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Cui-Lan Tang, PhD, Professor, Department of Infectious Diseases, The Second Affiliated Hospital of Zhejiang University School of Medicine, No. 88 Jiefang Road, Hangzhou 318000, Zhejiang Province, China. 2317001@zju.edu.cn
Received: February 24, 2024 Revised: May 16, 2024 Accepted: June 7, 2024 Published online: July 26, 2024 Processing time: 126 Days and 18.1 Hours
Abstract
BACKGROUND
Primary hepatic lymphoma (PHL) is a lymphoproliferative disorder confined to the liver without peripheral lymph node involvement and bone marrow invasion. PHL is extremely rare in clinical practice. The etiology and pathogenesis of PHL are largely unknown. There are no common standard protocols or guidelines for the treatment of PHL.
CASE SUMMARY
We report the case of a 66-year-old man who presented with fever and abdominal pain for three weeks. Computed tomography and magnetic resonance imaging scans showed a pyogenic liver abscess. The patient underwent a right posterior hepatectomy. The surgical pathology revealed aggressive B-cell lymphoma, with a primary consideration of diffuse large B-cell lymphoma of non-germinal center origin.
CONCLUSION
This article reviews the characteristics, mechanism and treatment of PHL and provides insight into the diagnosis of PHL.
Core Tip: We report a patient with liver abscess as the main manifestation. Repeated anti-infection treatment was not effective, and the patient was finally diagnosed with primary hepatic lymphoma (PHL) after surgical laparotomy. This report provides further insights into the diagnosis and treatment of PHL.
