Published online Jul 16, 2024. doi: 10.12998/wjcc.v12.i20.4412
Revised: May 4, 2024
Accepted: May 24, 2024
Published online: July 16, 2024
Processing time: 87 Days and 19.2 Hours
Cases of severe inflammatory renal disease and renal cell carcinoma (RCC) that occur simultaneously in the same kidney have been occasionally reported. However, extrarenal RCC that does not originate from the native kidney has rarely been reported. To our knowledge, this is the first reported case of RCC developing in the ipsilateral retroperitoneal space after a simple nephrectomy (SN) for inflammatory renal disease.
A 63-year-old woman was referred to our hospital following the incidental discovery of a left retroperitoneal mass without specific symptoms. Her medical history revealed a left SN 27 years ago due to a renal abscess. Magnetic resonance imaging of the abdomen revealed three oval masses in the left retroperitoneum. The masses were successfully excised, and subsequent pathology confirmed papillary RCC. After surgery, the patient remained disease-free for 11 years without adjuvant therapy.
Clinicians should be vigilant of RCC in patients with retroperitoneal masses, especially after SN for inflammatory renal disease.
Core Tip: To date, no cases of renal cell carcinoma (RCC) arising in the ipsilateral retroperitoneum following simple nephrectomy (SN) have been reported. We aimed to share our experience of treating RCC in the ipsilateral retroperitoneum of a 63-year-old Asian woman who underwent SN for a renal abscess 27 years ago. When evaluating retroperitoneal masses in patients with a positive clinical history of SN, clinicians should consider the possibility of late-onset RCC as a differential diagnosis.