Observational Study
Copyright ©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Jul 16, 2024; 12(20): 4217-4229
Published online Jul 16, 2024. doi: 10.12998/wjcc.v12.i20.4217
Intervention control of aerobic exercise in maintaining quality of life and pulmonary hypertension in hemodialysis patients
Dan-Dan Wang, Min Cheng, Chun-Ying Chen
Dan-Dan Wang, Chun-Ying Chen, Department of Rehabilitation Medicine, Zhejiang Hospital, Hangzhou 310012, Zhejiang Province, China
Min Cheng, Blood Purification Center, Zhejiang Hospital, Hangzhou 310012, Zhejiang Province, China
Author contributions: Wang DD designed the study; Cheng M performed the data collection and analysed the data; Wang DD and Chen CY wrote the manuscript; All authors reviewed the manuscript.
Supported by Zhejiang Province Medicine and Health Science and Technology Programme, No. 2019RC092 and No. 2020KY394; and the Public Welfare Project of Zhejiang Provincial Department of Science and Technology, No. LGF19H170003.
Institutional review board statement: This study was reviewed and approved by the Institutional Review Board of Medical Ethics Committee Zhejiang Hospital.
Informed consent statement: The present study was retrospective in nature and was approved by the Medical Ethics Committee Zhejiang Hospital, which had waived the signing of the informed consent form.
Conflict-of-interest statement: All authors confirm that there is no conflict of interest.
Data sharing statement: For original data, please contact the corresponding author for access.
STROBE statement: The authors have read the STROBE Statement—checklist of items, and the manuscript was prepared and revised according to the STROBE Statement—checklist of items.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Chun-Ying Chen, BMed, Associate Chief Nurse, Department of Rehabilitation Medicine, Zhejiang Hospital, No. 1229 Gudun Road, Hangzhou 310012, Zhejiang Province, China. zhang13656662318@163.com
Received: March 20, 2024
Revised: May 10, 2024
Accepted: May 23, 2024
Published online: July 16, 2024
Processing time: 102 Days and 2.6 Hours
Abstract
BACKGROUND

Pulmonary hypertension is a serious complication in the treatment of maintenance hemodialysis patients, which seriously affects the quality of life of patients and threatens their life safety. Prevention, treatment and improvement of pulmonary hypertension are of great significance to improve the quality of life of patients.

AIM

To investigate the intervention and control of pedal-powered bicycle in maintaining quality of life and pulmonary hypertension in hemodialysis patients.

METHODS

73 patients with maintenance hemadialysis combined with pulmonary arterial hypertension at a hemodialysis center in a certain hospital from May 2021 to May 2022 are selected. Patients are divided into two groups, 37 cases in the control group (group C) and 36 cases in the intervention group (group I). Patients are divided into two groups, group C is treated with oral administration of betaglandin sodium combined with routine nursing care. Based on group C, group I conducts power cycling exercises.

RESULTS

After treatment, group I patients had higher muscle strength, 36-Item Short Form Health Survey scores, and Kidney Disease Targets Areas scores; The 6-minute walk distance test index level was higher and the Borg score was lower; The group I had lower systolic blood pressure, greater vital capacity, higher positive emotion, lower systolic pulmonary artery pressure index level, higher arterial partial oxygen pressure level, lower pulmonary vascular resistance index level, and higher blood oxygen saturation level [158.91 ± 11.89 vs 152.56 ± 12.81, 1795.01 ± 603.18 vs 1907.20 ± 574.15, 24.00 (22.00, 29.00) vs 24.00 (22.00, 28.00), P < 0.001].

CONCLUSION

Aerobic exercise combined with Western medicine treatment can effectively improve patients' pulmonary hypertension, alleviate their negative emotions, and enable them to achieve a higher level of quality of life.

Keywords: Aerobic exercise, Hemodialysis, Pulmonary arterial hypertension, Cycle ergometer, Quality of life

Core Tip: This study investigates the effects of aerobic exercise, on the quality of life and pulmonary arterial hypertension (PAH) in patients undergoing hemodialysis. Employing a control design, the research divides patients into a control group receiving standard care and an intervention group undertaking power cycling in addition to standard care. The results demonstrate significant improvements in the intervention group, including enhanced muscle strength, better quality of life scores, reduced systolic blood pressure, and improved pulmonary function indicators. Incorporating aerobic exercise into the care regimen of hemodialysis patients with PAH can significantly improve their health outcomes and quality of life.