He W, Cheng Q. Risk factors and management countermeasures for obstructive sleep apnea hypoventilation syndrome in children. World J Clin Cases 2024; 12(20): 4041-4047 [PMID: 39015923 DOI: 10.12998/wjcc.v12.i20.4041]
Corresponding Author of This Article
Qi Cheng, MD, Doctor, Department of Pediatric Otolaryngology, Anhui Children's Hospital, Room 2006, Building 9, Wangjiang Garden, Baohe District, Hefei 240000, Anhui Province, China. lih90162hao@163.com
Research Domain of This Article
Otorhinolaryngology
Article-Type of This Article
Case Control Study
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Clin Cases. Jul 16, 2024; 12(20): 4041-4047 Published online Jul 16, 2024. doi: 10.12998/wjcc.v12.i20.4041
Risk factors and management countermeasures for obstructive sleep apnea hypoventilation syndrome in children
Wen He, Qi Cheng
Wen He, Qi Cheng, Department of Pediatric Otolaryngology, Anhui Children's Hospital, Hefei 240000, Anhui Province, China
Author contributions: He W and Cheng Q designed the research study; He W and Cheng Q performed the research; He W analyzed the data and wrote the manuscript; all authors have read and approved the final manuscript.
Institutional review board statement: The study was reviewed and approved by the [Anhui Children's Hospital] Institutional Review Board.
Informed consent statement: All study participants or their legal guardian provided informed written consent about personal and medical data collection prior to study enrolment.
Conflict-of-interest statement: All authors have no conflicts of interest.
Data sharing statement: No additional data are available.
STROBE statement: The authors have read the STROBE statement-checklist of items, and the manuscript was prepared and revised according to the STROBE statement-checklist of items.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Qi Cheng, MD, Doctor, Department of Pediatric Otolaryngology, Anhui Children's Hospital, Room 2006, Building 9, Wangjiang Garden, Baohe District, Hefei 240000, Anhui Province, China. lih90162hao@163.com
Received: April 1, 2024 Revised: May 3, 2024 Accepted: May 22, 2024 Published online: July 16, 2024 Processing time: 90 Days and 16.3 Hours
Abstract
BACKGROUND
Obstructive sleep apnea hypoventilation syndrome (OSAHS) in children is a sleep respiratory disorder characterized by a series of pathophysiologic changes. Statistics in recent years have demonstrated an increasing yearly incidence.
AIM
To investigate the risk factors for OSAHS in children and propose appropriate management measures.
METHODS
This study had a case–control study design. Altogether, 85 children with OSAHS comprised the case group, and healthy children of the same age and sex were matched at 1:1 as the control group. Basic information, including age, sex, height, weight and family history, and medical history data of all study participants were collected. Polysomnography was used to detect at least 8 h of nocturnal sleep. All participants were clinically examined for the presence of adenoids, enlarged tonsils, sinusitis, and rhinitis.
RESULTS
The analysis of variance revealed that the case group had a higher proportion of factors such as adenoid grading, tonsil indexing, sinusitis, and rhinitis than the control group.
CONCLUSION
A regression model was established, and glandular pattern grading, tonsil indexing, sinusitis, and pharyngitis were identified as independent risk factors affecting OSAHS development.
Core Tip: This case-control study of 85 children with obstructive sleep apnea hypoventilation syndrome (OSAHS) and matched healthy controls identified adenoid grading, tonsil indexing, sinusitis, and rhinitis as independent risk factors for OSAHS development using polysomnography and clinical examination.
