Zhu SZ, Gao ZF, Liu XR, Wang XG, Chen F. Surgically treating a rare and asymptomatic intraductal papillary neoplasm of the bile duct: A case report. World J Clin Cases 2024; 12(2): 367-373 [PMID: 38313650 DOI: 10.12998/wjcc.v12.i2.367]
Corresponding Author of This Article
Xiao-Guang Wang, Doctor, Academic Editor, Doctor, Department of Hepatobiliary Surgery, Jiaxing Second Hospital, No. 1518 Huancheng North Road, Nanhu District, Jiaxing 314000, Zhejiang Province, China. xiaoguangwangs@163.com
Research Domain of This Article
Surgery
Article-Type of This Article
Case Report
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Shen-Zhen Zhu, Department of General Surgery, Jiaxing Second Hospital, Jiaxing 314000, Zhejiang Province, China
Zhao-Feng Gao, Xiao-Rong Liu, Xiao-Guang Wang, Fei Chen, Department of Hepatobiliary Surgery, Jiaxing Second Hospital, Jiaxing 314000, Zhejiang Province, China
Co-corresponding authors: Xiao-Guang Wang and Fei Chen.
Author contributions: Gao ZF contributed to the treatment of cases and provided figures; Zhu SZ researched the data and wrote the manuscript; Liu XR contributed to the discussion; Chen F and Wang XG guided the writing ideas and reviewed the manuscript. All authors have read and approved the final version of the manuscript. Wang XG and Chen F contributed equally to this work as co-corresponding authors. The reasons for designating Wang XG and Chen F as co-corresponding authors are threefold. First, they provided great insights throughout the revision and improvement of the manuscript. Second, they helped the team to obtain support from relevant funds. Third, they also rationalized the assignment of tasks to our whole team, and the selection of them as co-corresponding authors recognizes and respects their equal contributions and commends the collaborative spirit of our research team. All the members agreed to designate Wang XG and Chen F as the co-corresponding authors.
Supported byZhejiang Provincial Natural Science Foundation of China Under Grant, No. LY21H160046.
Informed consent statement: Informed written consent was obtained from the patient for publication of this report and any accompanying images.
Conflict-of-interest statement: The authors declare that they have no conflict of interest.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Xiao-Guang Wang, Doctor, Academic Editor, Doctor, Department of Hepatobiliary Surgery, Jiaxing Second Hospital, No. 1518 Huancheng North Road, Nanhu District, Jiaxing 314000, Zhejiang Province, China. xiaoguangwangs@163.com
Received: September 7, 2023 Peer-review started: September 7, 2023 First decision: November 20, 2023 Revised: November 28, 2023 Accepted: December 26, 2023 Article in press: December 26, 2023 Published online: January 16, 2024 Processing time: 125 Days and 21.5 Hours
Abstract
BACKGROUND
Intraductal papillary neoplasms of the bile duct (IPNBs) are rare and characterized by papillary growth within the bile duct lumen. IPNB is similar to obstructive biliary pathology. In this report, we present an unexpected case of asymptomatic IPNB and consolidate our findings with the relevant literature to augment our understanding of this condition. Integrating relevant literature contributes to a more comprehensive understanding of the disease.
CASE SUMMARY
A 66-year-old Chinese male patient was admitted to our hospital for surgical intervention after gallstones were discovered during a routine physical examination. Preoperative imaging revealed a lesion on the left side of the liver, which raised the suspicion of IPNB. A laparoscopic left hemihepatectomy was performed, and subsequent histopathological examination confirmed the diagnosis of IPNB. At the 3-mo postoperative follow-up, the patient reported good recovery and no metastasis. IPNB can manifest both latently and asymptomatically. Radical surgical resection is the most effective treatment for IPNB.
CONCLUSION
Hepatic and biliary masses, should be considered to diagnose IPNB. Prompt surgery and vigilant follow-up are crucial in determining prognosis.
Core Tip: Intraductal papillary neoplasms are relatively uncommon in clinical practice, often eluding detection by clinicians owing to the inadequacy of conventional imaging tests such as abdominal ultrasound and computed tomography, to identify and diagnose tumors. In the present case, the patient was asymptomatic. However, if the tumor was not detected and resected promptly, the patient could have lost the opportunity for surgical intervention when developing relevant biliary symptoms. Early detection and surgical intervention hold promise for a positive prognosis. Clinicians must further enhance their understanding of the clinical attributes and imaging indications to prevent missed diagnoses.
