Tan SD, Li MH. Brain abscess caused by Streptococcus anginosus group: Three case reports. World J Clin Cases 2024; 12(17): 3243-3252 [PMID: 38898852 DOI: 10.12998/wjcc.v12.i17.3243]
Corresponding Author of This Article
Ming-Hui Li, FAASLD, Chief Doctor, Department of Infection, Shaoxing People's Hospital, Yuecheng Lingzhi Street Zhongxing North Road, Shaoxing 312000, Zhejiang Province, China. liminghui@zju.edu.cn
Research Domain of This Article
Infectious Diseases
Article-Type of This Article
Case Report
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Clin Cases. Jun 16, 2024; 12(17): 3243-3252 Published online Jun 16, 2024. doi: 10.12998/wjcc.v12.i17.3243
Brain abscess caused by Streptococcus anginosus group: Three case reports
Si-Di Tan, Ming-Hui Li
Si-Di Tan, The 2nd Clinical Medical College, Zhejiang Chinese Medical University, Hangzhou 310053, Zhejiang Province, China
Ming-Hui Li, Department of Infection, Shaoxing People's Hospital, Shaoxing 312000, Zhejiang Province, China
Author contributions: Tan SD collected data and materials, selected appropriate cases, summarized commonalities, edited images, arranged layouts, translated and drafted the initial manuscript, and conducted literature analysis and review. Li MH provided ideas and directions, revised the initial draft, and supplied the necessary data and materials.
Supported by2024 Zhejiang Province Traditional Chinese Medicine Science and Technology Plan, No. 2024ZL1129 and No. 2024ZL1130.
Informed consent statement: Written informed consent was obtained from the patients for publication of this report and any accompanying images.
Conflict-of-interest statement: The authors declare no conflicts of interest.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Ming-Hui Li, FAASLD, Chief Doctor, Department of Infection, Shaoxing People's Hospital, Yuecheng Lingzhi Street Zhongxing North Road, Shaoxing 312000, Zhejiang Province, China. liminghui@zju.edu.cn
Received: February 29, 2024 Revised: April 28, 2024 Accepted: May 17, 2024 Published online: June 16, 2024 Processing time: 96 Days and 7.7 Hours
Abstract
BACKGROUND
This case series investigated the clinical manifestations, diagnoses, and treatment of cerebral abscesses caused by Streptococcus anginosus. We retrospectively analyzed the clinical characteristics and outcomes of three cases of cerebral abscesses caused by Streptococcus anginosus and conducted a comprehensive review of relevant literature.
CASE SUMMARY
Case 1 presented with a history of left otitis media and exhibited high fever, confusion, and vomiting as primary symptoms. Postoperative pus culture indicated a brain abscess caused by Streptococcus constellatus infection. Case 2 experienced dizziness for two days as the primary symptom. Postoperative pus culture suggested an intermediate streptococcal brain abscess. Case 3: Enhanced head magnetic resonance imaging (MRI) and diffusion-weighted imaging revealed occupancy of the left temporal lobe, initially suspected to be a metastatic tumor. However, a postoperative pus culture confirmed the presence of a brain abscess caused by Streptococcus anginosus infection. The three cases presented in this case series were all patients with community-acquired brain abscesses resulting from angina caused by Streptococcus group infection. All three patients demonstrated sensitivity to penicillin, ceftriaxone, vancomycin, linezolid, chloramphenicol, and levofloxacin. Successful treatment was achieved through stereotaxic puncture, drainage, and ceftriaxone administration with a six -week course of antibiotics.
CONCLUSION
Preoperative enhanced head MRI plays a critical role in distinguishing brain tumors from abscesses. Selecting the correct early diagnostic methods for brain abscesses and providing timely intervention are very important. This case series was in accordance with the CARE guidelines.
Core Tip: Brain abscess patients are often at risk and the condition can be fatal. Several complications might arise after cure; therefore, early diagnosis and timely treatment intervention are particularly important in order to improve the prognosis of brain abscess patients. However, the early diagnosis of brain abscesses is always difficult. We reviewed and analyzed specific treatment processes and early diagnosis of three cases of brain abscesses caused by Streptococcus anginosus.
