Sun MQ, Kang XM, He XD, Han XL. Laparoscopic spleen-preserving total pancreatectomy for the treatment of low-grade malignant pancreatic tumors: Two case reports and review of literature. World J Clin Cases 2024; 12(17): 3206-3213 [PMID: 38898831 DOI: 10.12998/wjcc.v12.i17.3206]
Corresponding Author of This Article
Xian-Lin Han, MD, Surgeon, Department of General Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, No. 1 Shuai Fu Yuan, Dongcheng District, Beijing 100730, China. hanxianlin@pumch.cn
Research Domain of This Article
Surgery
Article-Type of This Article
Case Report
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Clin Cases. Jun 16, 2024; 12(17): 3206-3213 Published online Jun 16, 2024. doi: 10.12998/wjcc.v12.i17.3206
Laparoscopic spleen-preserving total pancreatectomy for the treatment of low-grade malignant pancreatic tumors: Two case reports and review of literature
Meng-Qing Sun, Xiao-Man Kang, Xiao-Dong He, Xian-Lin Han
Meng-Qing Sun, Xiao-Man Kang, Xiao-Dong He, Xian-Lin Han, Department of General Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing 100730, China
Author contributions: Sun MQ is responsible for collecting case data, creating illustrations, and writing the manuscript; Kang XM is responsible for manuscript editing, translation, and language polishing; He XD provides technical support and guidance for case management; Han XL provides the case, performs the surgery, and is fully responsible for case management throughout.
Supported byNational High Level Hospital Clinical Research Funding, No. 2022-PUMCH-B-003; and National Multidisciplinary Cooperative Diagnosis and Treatment Capacity Building Project for Major Diseases.
Informed consent statement: Informed written consent for the treatment was obtained from the patients.
Conflict-of-interest statement: There are no competing interests.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Xian-Lin Han, MD, Surgeon, Department of General Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, No. 1 Shuai Fu Yuan, Dongcheng District, Beijing 100730, China. hanxianlin@pumch.cn
Received: February 17, 2024 Revised: April 4, 2024 Accepted: April 18, 2024 Published online: June 16, 2024 Processing time: 108 Days and 15.2 Hours
Abstract
BACKGROUND
Function-preserving pancreatectomy can improve the long-term quality of life of patients with benign or low-grade malignant tumors, such as intraductal papillary mucinous neoplasms (IPMNs) and mucinous cystic neoplasms. However, there is limited literature on laparoscopic spleen-preserving total pancreatectomy (L-SpTP) due to technical difficulties.
CASE SUMMARY
Patient 1 was a 51-year-old male diagnosed with IPMN based on preoperative imaging, showing solid nodules in the pancreatic head and diffuse dilation of the main pancreatic duct with atrophy of the distal pancreas. We performed L-SpTP with preservation of the splenic vessels, and the postoperative pathology report revealed IPMN with invasive carcinoma. Patient 2 was a 60-year-old male with multiple cystic lesions in the pancreatic head and body. L-SpTP was performed, and intraoperatively, the splenic vein was injured and required ligation. Postoperative pathology revealed a mucinous cystic tumor of the pancreas with low-grade dysplasia. Both patients were discharged on postoperative day 7, and there were no major complications during the perioperative period.
CONCLUSION
We believe that L-SpTP is a safe and feasible treatment for low-grade malignant pancreatic tumors, but more case studies are needed to evaluate its safety, efficacy, and long-term outcomes.
Core Tip: Spleen-preserving total pancreatectomy (SpTP) can provide patients with a higher long-term quality of life for benign or low-grade malignant pancreatic tumors. However, there is limited literature on laparoscopic SpTP due to technical difficulties. This article reports two cases of laparoscopi SpTP (LSpTP). The postoperative pathology reports showed intraductal papillary mucinous neoplasms and mucinous cystic neoplasm, respectively. Both patients had no major complications during the perioperative period. We believe that LSpTP is a safe and feasible treatment for low-grade malignant pancreatic tumors.
