Randomized Clinical Trial
Copyright ©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Jun 16, 2024; 12(17): 3086-3093
Published online Jun 16, 2024. doi: 10.12998/wjcc.v12.i17.3086
Effects of psychological nursing in Parkinson's related depression patients undergoing functional magnetic resonance imaging: A randomized controlled trial
Xiao-Xia Zhang, Xiao-Hui Zhang, Yan-Chao Dong
Xiao-Xia Zhang, Department of Internal Medicine, The First hospital of Qinhuangdao, Qinhuangdao 066000, Hebei Province, China
Xiao-Hui Zhang, Department of Gastroscope, The First hospital of Qinhuangdao, Qinhuangdao 066000, Hebei Province, China
Yan-Chao Dong, Medical Imaging Center, The First hospital of Qinhuangdao, Qinhuangdao 066000, Hebei Province, China
Author contributions: Zhang XX and Dong YC contributed to the design of the study and the development of the study protocol; Zhang XX and Dong YC coordinated the study; Zhang XH and Dong YC performed the systematic review, including data collection and data analysis; All authors contributed to data interpretation, manuscript drafting and review; Dong YC drafted the first version of the manuscript.
Supported by Qinhuangdao Science-Technology Support Projects of China, No. 202101A141.
Institutional review board statement: The study was reviewed and approved by the First hospital of Qinhuangdao Institutional Review Board, No. 2017A021.
Clinical trial registration statement: The study has been registered with the Chinese Clinical Trial Registry with registration number ChiCTR1900024027.
Informed consent statement: All subjects understood and agreed to the study protocol and voluntarily signed the informed consent form.
Conflict-of-interest statement: The authors declare that they have no conflict of interest.
Data sharing statement: No additional data are available.
CONSORT 2010 statement: The authors have read the CONSORT 2010 statement, and the manuscript was prepared and revised according to the CONSORT 2010 statement.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Yan-Chao Dong, MD, Doctor, Medical Imaging Center, The First hospital of Qinhuangdao, No. 258 Wenhua Road, Qinhuangdao 066000, Hebei Province, China. dyc_hometown@aliyun.com
Received: February 20, 2024
Revised: April 11, 2024
Accepted: April 23, 2024
Published online: June 16, 2024
Processing time: 105 Days and 5 Hours
Abstract
BACKGROUND

Patients with Parkinson’s disease (PD) often experience depression, and some may require magnetic resonance imaging (MRI) for diagnosis, which can lead to MRI failure due to claustrophobia.

AIM

To explore the value of psychological interventions in successfully completing functional MRI scans of the brain for PD-related depression.

METHODS

Ninety-six patients with PD were randomly divided into two groups. The control group (47 patients) received general care, and the experimental group (49 patients) received general care combined with psychological care. The Unified Parkinson's Disease Assessment Scale (UPDRS), Hamilton Depression Scale (HAMD), and Geriatric Depression Scale (GDS)-15 scores, heart rate, systolic blood pressure, and MRI-Anxiety Questionnaire (MRI-AQ) scores before and after the scan were recorded. The completion rate of magnetic resonance (MR) scanning, scanning duration, and image quality scores were recorded.

RESULTS

Before scanning, no statistically significant difference was observed between the two groups in terms of heart rate, systolic blood pressure, and UPDRS, HAMD, GDS-15, and MRI-AQ scores. After scanning, systolic blood pressure, MRI-AQ score, and scan time in the experimental group were significantly lower than those in the control group, whereas the scan completion rate and image quality score were significantly higher than those in the control group.

CONCLUSION

Psychological nursing interventions are helpful in alleviating PD-related depression and assessing MR depression scores and may be helpful in the successful completion of functional MRI scans of the patient's brain.

Keywords: Magnetic resonance imaging; Psychological nursing; Parkinson's disease; Depression; Claustrophobia

Core Tip: This study investigates the prevalence of depression among Parkinson’s disease (PD) patients, highlighting its significant impact on psychological well-being. Functional magnetic resonance imaging (MRI) plays a crucial role in PD diagnosis, yet patients often experience anxiety during scans due to unfamiliarity and discomfort. Psychological nursing interventions can alleviate anxiety, enhancing patients' ability to undergo MRI scans successfully. The study reveals correlations between anxiety levels, PD severity, and MRI-related depression scores. Psychological nursing significantly reduces blood pressure spikes post-scan and improves completion rates and image quality. Despite limitations like small sample sizes, multi-center studies are proposed for future validation of findings.