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World J Clin Cases. Jun 16, 2024; 12(17): 2946-2950
Published online Jun 16, 2024. doi: 10.12998/wjcc.v12.i17.2946
Advances in the application of auxiliary imaging techniques in parathyroid diseases
Lei Lu, Hong-Qing Shang
Lei Lu, Hong-Qing Shang, Department of Breast and Thyroid Surgery, Beijing Haidian Hospital, Beijing 100080, China
Author contributions: Lu L and Shang HQ designed the research study, performed the research, contributed new reagents and analytic tools, analyzed the data and wrote the manuscript; all authors have read and approve the final manuscript.
Supported by The 2024 Hospital Research Funding, No. KYQ2024008.
Conflict-of-interest statement: The authors have no conflicts of interest to declare.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Hong-Qing Shang, MD, Surgeon, Department of Breast and Thyroid Surgery, Beijing Haidian Hospital, No. 29 Zhongguancun Street, Haidian District, Beijing 100080, China. 475758774@qq.com
Received: December 30, 2023
Revised: April 25, 2024
Accepted: May 6, 2024
Published online: June 16, 2024
Processing time: 157 Days and 0.9 Hours
Abstract

Hypoparathyroidism is one of the main complications after total thyroidectomy, severely affecting patients’ quality of life. How to effectively protect parathyroid function after surgery and reduce the incidence of hypoparathyroidism has always been a key research area in thyroid surgery. Therefore, precise localization of parathyroid glands during surgery, effective imaging, and accurate surgical resection have become hot topics of concern for thyroid surgeons. In response to this clinical phenomenon, this study compared several different imaging methods for parathyroid surgery, including nanocarbon, indocyanine green, near-infrared imaging techniques, and technetium-99m methoxyisobutylisonitrile combined with gamma probe imaging technology. The advantages and disadvantages of each method were analyzed, providing scientific recommendations for future parathyroid imaging. In recent years, some related basic and clinical research has also been conducted in thyroid surgery. This article reviewed relevant literature and provided an overview of the practical application progress of various imaging techniques in parathyroid surgery.

Keywords: Imaging technique; Parathyroid gland; Thyroid surgery; Hypoparathyroidism; Complication

Core Tip: Hypoparathyroidism is one of the main complications after radical thyroidectomy, which seriously affects the quality of life. How to effectively protect parathyroidism and reduce the incidence of hypoparathyroidism has been a key research field in thyroid surgery. In view of this clinical phenomenon, this study introduced different methods of parathyroid imaging during surgery, analyzed their advantages and disadvantages, and provided scientific suggestions for subsequent parathyroid imaging.