Kou MQ, Xu BQ, Liu HT. Multimodal imaging in the diagnosis of bone giant cell tumors: A retrospective study. World J Clin Cases 2024; 12(16): 2722-2728 [PMID: 38899310 DOI: 10.12998/wjcc.v12.i16.2722]
Corresponding Author of This Article
Hui-Tong Liu, MD, PhD, Attending Doctor, Surgeon, Department of Orthopedics, Shaanxi Provincial People's Hospital, No. 256 Youyi West Road, Beilin District, Xi'an 710068, Shaanxi Province, China. liuhuitong@126.com
Research Domain of This Article
Radiology, Nuclear Medicine & Medical Imaging
Article-Type of This Article
Retrospective Study
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Clin Cases. Jun 6, 2024; 12(16): 2722-2728 Published online Jun 6, 2024. doi: 10.12998/wjcc.v12.i16.2722
Multimodal imaging in the diagnosis of bone giant cell tumors: A retrospective study
Ming-Qing Kou, Bing-Qiang Xu, Hui-Tong Liu
Ming-Qing Kou, Bing-Qiang Xu, Department of Medical Imaging, Shaanxi Provincial People's Hospital, Xi'an 710068, Shaanxi Province, China
Hui-Tong Liu, Department of Orthopedics, Shaanxi Provincial People's Hospital, Xi'an 710068, Shaanxi Province, China
Author contributions: Kou MQ, Xu BQ and Liu HT designed the research; Kou MQ, Xu BQ and Liu HT performed the research; Kou MQ and Xu BQ collected, evaluated and analyzed the data; Liu HT reviewed all the medical record; Kou MQ and Xu BQ drafted the initial manuscript, Liu HT reviewed the manuscript; All authors read and approved the final manuscript.
Supported bythe Technology Innovation Leading Program of Shaanxi, No. 2023KXJ-095; the Shaanxi Provincial People's Hospital Science and Technology Talent Support Program for Elite Talents, No. 2021JY-38 and No. 2021JY-50; and the Shaanxi Provincial People's Hospital Science and Technology Development Incubation Foundation, No. 2023YJY-39.
Institutional review board statement: The study protocol was approved by the Medical Ethical Committee of Shaanxi Provincial People’s Hospital (2020-07-15).
Informed consent statement: Informed consent was exempted due to the retrospective design of this study.
Conflict-of-interest statement: All authors declare that they have no conflicts of interest, financial or otherwise.
Data sharing statement: The authors confirm that the data supporting the findings of this study are available within the article.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Hui-Tong Liu, MD, PhD, Attending Doctor, Surgeon, Department of Orthopedics, Shaanxi Provincial People's Hospital, No. 256 Youyi West Road, Beilin District, Xi'an 710068, Shaanxi Province, China. liuhuitong@126.com
Received: December 22, 2023 Revised: February 21, 2024 Accepted: April 18, 2024 Published online: June 6, 2024 Processing time: 159 Days and 1.2 Hours
Abstract
BACKGROUND
Giant cell tumor of bone is a locally aggressive and rarely metastasizing tumor, and also a potential malignant tumor that may develop into a primary malignant giant cell tumor.
AIM
To evaluate the role of multimodal imaging in the diagnosis of giant cell tumors of bone.
METHODS
The data of 32 patients with giant cell tumor of bone confirmed by core-needle biopsy or surgical pathology at our hospital between March 2018 and March 2023 were retrospectively selected. All the patients with giant cell tumors of the bone were examined by X-ray, computed tomography (CT) and magnetic resonance imaging (MRI), and 7 of them were examined by positron emission tomography (PET)-CT.
RESULTS
X-ray imaging can provide overall information on giant cell tumor lesions. CT and MRI can reveal the characteristics of the internal structure of the tumor as well as the adjacent relationships of the tumor, and these methods have unique advantages for diagnosing tumors and determining the scope of surgery. PET-CT can detect small lesions and is highly valuable for identifying benign and malignant tumors to aid in the early diagnosis of metastasis.
CONCLUSION
Multimodal imaging plays an important role in the diagnosis of giant cell tumor of bone and can provide a reference for the treatment of giant cell tumors.
Core Tip: Multimodal imaging plays an important role in the diagnosis of giant cell tumors. X-ray, computed tomography, magnetic resonance imaging, and positron emission tomography-computed tomography imaging have their own advantages and can provide a reference for the treatment of giant cell tumors.
