Published online May 26, 2024. doi: 10.12998/wjcc.v12.i15.2672
Revised: March 15, 2024
Accepted: April 3, 2024
Published online: May 26, 2024
Processing time: 81 Days and 22.8 Hours
Paraganglioma (PGL) located in the retroperitoneum presents challenges in diagnosis and treatment due to its hidden location, lack of specific symptoms in the early stages, and absence of distinctive manifestations on imaging.
A 56-year-old woman presented with a left upper abdominal mass discovered 1 wk ago during a physical examination. She did not have a history of smoking, alcohol consumption, or other harmful habits, no surgical procedures or infectious diseases, and had a 4-year history of hypertension. Upon admission, she did not exhibit fever, vomiting, or abdominal distension. Physical examination indicated mild percussion pain in the left upper abdomen, with no palpable enlargement of the liver or spleen. Laboratory tests and tumor markers showed no significant abnormalities. Enhanced computed tomography and magnetic resonance imaging of the upper abdomen revealed a cystic solid mass in the left epigastrium measuring approximately 6.5 cm × 4.5 cm, with inhomogeneous enhancement in the arterial phase, closely associated with the lesser curvature of the stomach and the pancreas. The patient underwent laparoscopic resection of the retroperitoneal mass, which was successfully removed without tumor rupture. A 12-month postoperative follow-up period showed good recovery.
This case report details the successful laparoscopic resection of a retroperitoneal subclinical PGL, resulting in a good recovery observed at the 12-month follow-up. Interestingly, the patient also experienced unexpected cure of hypertensive disease.
Core Tip: Retroperitoneal subclinical paragangliomas (PGLs) are exceptionally uncommon. In this report, we present a case of PGL that was effectively managed by laparoscopic retroperitoneal lumpectomy. The patient showed excellent recovery at the 12-month postoperative follow-up and notably experienced resolution of her hypertensive condition. The management of this case serves as a valuable reference for addressing retroperitoneal PGLs.